24 results
Warm vs Cold Autoimmune Hemolytic Anemia
Warm Autoimmune Hemolytic Anemia:
 • Mechanism: IgG and Complement-mediated
 • Etiology:
Spherocytes • Treatment ... disorder, Mycoplasma, HIV ... , EBV • Associated ... transient hemolysis • Treatment ... #hematology #diagnosis
Chronic Hepatitis B - Diagnosis and Management Algorithm

• Who to treat: Essentially treat the pts with
Chronic Hepatitis ... B - Diagnosis and ... #Algorithm #Diagnosis ... #Management #Treatment ... #Hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
DILI) - Stepwise Diagnosis ... non-essential drug/HDS treatments ... , HBV, HCV, HEV, ... steatosis • Autoimmune ... #Algorithm #hepatology
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
- Differential Diagnosis ... : • Acute or Chronic ... effect following treatment ... Iron deficiency anemia ... Algorithm #Causes #Hematology
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
 • Thalassemia
- Differential Diagnosis ... Spherocytosis, G6PD, PK, HbC ... - Extrinsic: Autoimmune ... #Differential #Diagnosis ... #hematology
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
, Chronic disease ... spherocytosis, Autoimmune ... Agglutinate: Cold autoimmune ... #differential #diagnosis ... #hematology #microscopy
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
- Differential Diagnosis ... malignancies • Anemia ... hemorrhage) • Chronic ... disorders (e.g. autoimmune ... #Causes #hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor
The maturation factor is
of chronic inflammation ... deficiencies: Chronic ... • Hemolysis: Autoimmune ... Production #Index #hematology ... #diagnosis #calculation
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Chronic Lymphocytic ... minimal tumor burden Diagnosis ... 5) Symptoms of anemia ... Leukemia #oncology #hematology ... #hemeonc #diagnosis
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... hemolysis, deficiency anemia ... Rebound effect from treatment ... • Infections: Chronic ... #Algorithm #hematology