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diagnosis management differential erythematosus sle systemic algorithm hematology vasculitis ana antinuclear autoantibodies guidelines syndrome table acr2021 anca causes classification druginduced
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
Antineutrophil cytoplasmic antibodies ... ) • Systemic lupus ... ANCA+ 90% • Granulomatosis ... Antineutrophil #antibodies ... #diagnosis #rheumatology
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
Homogeneous: Systemic lupus ... , Drug-induced Lupus ... Speckled: Systemic lupus ... #Antinuclear #Antibodies ... ANA #patterns #rheumatology
Vasculitis Management - ACR/VF 2021 Guidelines for Treatment & Management • Giant Cell Arteritis (GCA) •
Guidelines for Treatment ... Nodosa (PAN) • Granulomatosis ... • Eosinophilic Granulomatosis ... Vasculitis #Management #Treatment ... Guidelines #algorithm #rheumatology
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... • Lupus (SLE): ... others (RNP, aPL antibodies ... glycoprotein I (ß2GP), Lupus ... Autoantibodies #Rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... Antibody refers to antibodies ... , Drug-induced Lupus ... #Antinuclear #Antibodies ... ANA #patterns #rheumatology
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
Criteria for Systemic Lupus ... Acute cutaneous lupus ... Class II or V lupus ... Highly specific antibodies ... Erythematosus #diagnosis #rheumatology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... SLE-Related Auto-Antibodies ... Diagnosis and Lupus ... : Drug-induced lupus ... #differential #rheumatology
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm Acute Kidney Injury (AKI) - Acute increase
Glomerulonephritis • Anti-GBM antibodies ... IgA, post-strep, lupus ... Pauci-immune (Granulomatosis ... legionella) • Immune (lupus
Antiphospholipid Syndrome (APS) APS is a rare autoimmune disorder characterized by recurring blood clots resulting from antibodies
resulting from antibodies ... Antiphospholipid antibodies ... (aPL): • Lupus ... glycoprotein I antibodies ... to be present Treatment
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
Post-strep GN, Lupus ... Purpura Anti-GBM antibodies ... diagnosis #algorithm #rheumatology
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