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differential hematology algorithm management workup lupus sle systemic dermatology dermatomyositis pancytopenia signs symptoms testing activation antimda5 antimda5dm antinxp2 antinxp2dm arthritis
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
Pancytopenia - Workup ... and Differential Diagnosis ... Acquired Aplastic Anemia ... Metastatic Disease ... #Algorithm #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
- Differential Diagnosis ... concerning for malignancy ... for workup, including ... hemolysis, deficiency anemia ... Vasculitides, IBD, Celiac disease
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... Non-autoimmune rheumatologic ... Infections • Malignancy ... lymphopenia, low PLT • Anemia ... #Diagnosis #Rheumatology
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
Pancytopenia - Workup ... and Differential Diagnosis ... Acquired Aplastic Anemia ... Metastatic Disease ... #Algorithm #Hematology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... - Hemolytic anemia ... Myositis 4% - Lung ... sclerosis, Still's disease ... #differential #rheumatology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential Diagnosis ... valve, vasculitis, malignant ... #Algorithm #workup ... #hematology #testing
Causes of Pericardial Effusion - Differential Diagnosis Infectious: • Viral: Enterovirus, Herpesvirus, Adenovirus, Parvovirus • Bacterial: Mycobacterium
- Differential Diagnosis ... Non-Infectious: • Rheumatologic ... , Takayasu Disease ... - Metastatic: Lung ... • Metabolic: Uremia
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
effusion, Restrictive lung ... pain (20%) Renal disease ... ) Blood (75%): Anemia ... signs #symptoms #diagnosis ... #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Systemic lupus erythematosus ... rash) • Heart, lung ... with leukopenia, anemia ... Activation #Syndrome #Diagnosis ... #Rheumatology
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
with edema • Erythematous ... severity of the disease ... anti-NXP2 Abs Lung ... Dermatomyositis #rheumatology ... #dermatology #diagnosis
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