9 results
Nephron Pathophysiology - Diuretic Sites of Action
Diuretics
1) Acetazolamide/canagliflozin
2) Osmotic agents (mannitol, urearetics)
3) Loop agents (eg, furosemide)
4)
Nephron Pathophysiology ... Osmotic agents (mannitol ... urearetics) 3) Loop ... Adenosine #Nephron ... #Pathophysiology
Hormones Acting on the Nephron - Diuretics and Their Site of Action
 1) Acetazolamide
 2) Osmotic
Acting on the Nephron ... Diuretics (e.g. mannitol ... ) 3) Loop Diuretics ... spironolactone) #Pathophysiology ... #Nephrology #Nephron
Diuretics sites of action on the nephron
1) Acetazolamide (carbonic anhydrase inhibitor)
2) Osmotic diuretics (e.g. mannitol)
3) Loop
action on the nephron ... diuretics (e.g. mannitol ... ) 3) Loop diuretic ... triamterene) #nephron ... pharmacology #nephrology #medications
Major Segments of the Nephron and their Functions 
 - Glomerulus - Formation of glomerular filtrate
Segments of the Nephron ... organic acids and bases ... limb of Henle's loop ... limb of Henle's loop ... Segments #Function #Pathophysiology
Diuretics - Pharmacology

Thiazides diuretics:
 • Inhibit Na+ Cl- cotransporter in distal tubule
 • Chlorothiazide, Chlorthalidone, Indapamide,
Metolazone Loop ... loss through the nephron ... ), Isosorbide, Mannitol ... nephrology #conversion #loop ... #thiazide #classes
Drugs associated with hypokalemia and hypomagnesemia

Hypokalemia
- Shift from extracellular fluid to intracellular fluid compartment
  -
Furosemide and other loop ... Thiazides - Mannitol ... hypomagnesemia #Medications ... diagnosis #nephrology #Causes
Pituitary Mass Effects - Pathogenesis and Clinical Findings
 • Pituitary turnors are almost always a benign
For pituitary masses ... targeted with medication ... hormones are is, "Go Look ... Headaches • Nausea ... mnemonic #GLFTAP #pathophysiology
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Osmotic Diuretics (Mannitol ... +2Cl- Symport (Loop ... Kidney stones caused ... #Pharmacology #Medications
Algorithm for Diagnosis and Management of Resistant Hypertension in CKD
Pseudoresistant Hypertension - Reduce barriers to adherence:
Algorithm for Diagnosis ... Use once-daily medications ... Consider other causes ... Add loop diuretic ... Hypertension #CKD #Algorithm