17 results
Nephron Pathophysiology - Diuretic Sites of Action
Diuretics
1) Acetazolamide/canagliflozin
2) Osmotic agents (mannitol, urearetics)
3) Loop agents (eg, furosemide)
4)
Nephron Pathophysiology ... Osmotic agents (mannitol ... urearetics) 3) Loop ... Adenosine #Nephron ... #Pathophysiology
Hormones Acting on the Nephron - Diuretics and Their Site of Action
 1) Acetazolamide
 2) Osmotic
Acting on the Nephron ... Diuretics (e.g. mannitol ... ) 3) Loop Diuretics ... spironolactone) #Pathophysiology ... #Nephrology #Nephron
Major Segments of the Nephron and their Functions 
 - Glomerulus - Formation of glomerular filtrate
Segments of the Nephron ... and their Functions ... organic acids and bases ... limb of Henle's loop ... #Pathophysiology
Causes of Peripheral Weakness - With and Without Sensory Changes - Differential Diagnosis Algorithm
With Sensory Changes:
Causes of Peripheral ... Mononeuropathy - Compression ... Weakness • Motor Neuron ... Neuromuscular Junction ... #Causes
NSAIDS and their effects on the Kidney - Pathophysiology

Arachidonic Acid metabolites into alternative pathways that modify
on the Kidney - Pathophysiology ... modify immune function ... reabsorption in Proximal, loop ... distal component of Nephron ... absorption in distal nephron
Diuretics - Pharmacology

Thiazides diuretics:
 • Inhibit Na+ Cl- cotransporter in distal tubule
 • Chlorothiazide, Chlorthalidone, Indapamide,
Metolazone Loop ... loss through the nephron ... ), Isosorbide, Mannitol ... nephrology #conversion #loop ... #thiazide #classes
Hypochloremia - Differential Diagnosis Algorithm

Cause - Decreased Intake:
 • Low salt in diet
 • Exclusive D5W
Differential Diagnosis Algorithm ... transport, renal function ... Gastrointestinal function ... Differential #Diagnosis #Algorithm ... #Pathophysiology
Pathophysiology - Renal compression as a mechanism of obesity hypertension. 
Compression of the thin loop of
Pathophysiology ... thin loop of Henle ... thick ascending loop ... individuals prior to nephron ... hypertension #obesity #pathophysiology
Causes of Peripheral Weakness without Sensory Changes - Differential Diagnosis Algorithm
No Objective Weakness
 • Cardio-pulmonary disease
Causes of Peripheral ... Differential Diagnosis Algorithm ... Disease Motor Neuron ... Neuromuscular Junction ... #Causes
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
loss of motor function ... Syndrome ->Cord compression ... loss of motor function ... and lower motor neuron ... Syndromes #diagnosis #pathophysiology