20 results
Nephron Pathophysiology - Diuretic Sites of Action
Diuretics
1) Acetazolamide/canagliflozin
2) Osmotic agents (mannitol, urearetics)
3) Loop agents (eg, furosemide)
4)
Nephron Pathophysiology ... Osmotic agents (mannitol ... urearetics) 3) Loop ... Adenosine #Nephron #Pathophysiology
Hormones Acting on the Nephron - Diuretics and Their Site of Action
 1) Acetazolamide
 2) Osmotic
Diuretics (e.g. mannitol ... ) 3) Loop Diuretics ... spironolactone) #Pathophysiology
Diuretic Electrolyte Excretion Effects 
Diuresis, Na+, K+, Mg2+, Ca2+, Cl-, HCO3-, Uric Acid
 - Thiazide Type
Diuretic Electrolyte Excretion ... Thiazide Type - Loop ... pharmacology #comparison #table
Summary of Diuretic Agents 
Subclass, Drug, Mechanism of Action, Effects, Clinical Applications, Pharmacokinetics, Toxicities, Interaction
CARBONIC ANHYDRASE
empagliflozin LOOP ... DIURETICS • Mannitol ... Pharmacology #summary #table
Diuretics - Pharmacology

Thiazides diuretics:
 • Inhibit Na+ Cl- cotransporter in distal tubule
 • Chlorothiazide, Chlorthalidone, Indapamide,
Metolazone Loop ... the nephron by excretion ... ), Isosorbide, Mannitol ... -promote water excretion ... nephrology #conversion #loop
Major Segments of the Nephron and their Functions 
 - Glomerulus - Formation of glomerular filtrate
straight segments - Secretion ... limb of Henle's loop ... limb of Henle's loop ... Segments #Function #Pathophysiology ... #Tubules #Table
Feedback Loop: Prolactin (PRL)
 • PRL levels exhibit diurnal, menstrual, and age-related variation
 • TRH has
Feedback Loop: Prolactin ... regulator of PRL secretion ... Hypothalamus -> Decr GnRH secretion ... endocrinology #pathophysiology
A schema of the pathophysiology of the inborn errors of metabolism, excluding complex storage diseases. Helps
schema of the pathophysiology ... connections and pathophysiology ... the lab values table ... #Diagnosis #Algorithm ... Peds #Pediatrics #Table
Magnesium Absorption and Pathophysiology 
Magnesium Absorption: 
 • absorbed in the GIT — small intestine, Saturable
Absorption and Pathophysiology ... red blood cell Excretion ... ascending limb of loop ... Magnesium #Absorption #Pathophysiology
Lab patterns seen in Inborn Errors of Metabolism

A table of lab values compiled from UpToDate and
Metabolism A table ... metabolicemergency-pathophysiology-differential-pediatrics-metabolism-algorithm-diagnosis ... Peds #Pediatrics #Table