15 results
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
(SLE) - Diagnosis ... • Immunologic Workup ... life-threatening • Treatment ... : Chronic disease ... Erythematosus #Diagnosis
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... Treatment: • ... #Systemic #Lupus ... #Summary #diagnosis ... #rheumatology #management
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... • Immunologic Workup ... : Chronic disease ... #rheumatology #diagnosis ... #management
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... Demyelinating Syndrome ... Cerebrovascular Disease ... Erythematosus #SLE ... #management #treatment
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
hematology for workup ... Rebound effect from treatment ... Vasculitides, IBD ... , Celiac disease ... Kawasaki, Nephrotic syndrome
Shock - Differential Diagnosis Framework
 - MAP <65. SBP <90, drop in SBP > 40
 -
, Severe Valve Disease ... Abdominal compartment syndrome ... #criticalcare # ... algorithm #treatment ... #management
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Medium and large ... Oral aphthae : SLE ... • Arthritis: SLE ... Arthritis, AS Treatment ... #diagnosis #management
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
• Systemic lupus ... SJIA], systemic lupus ... erythematosus [SLE ... Treatment: • Corticosteroids ... #Diagnosis #Management
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
life-threatening diseases ... Inflammatory eye disease ... mononeuritis multiplex WORKUP ... blood retum in serial ... #management #treatment
Peripartum Cardiomyopathy - Summary
1. Definition
 • Towards the end of pregnancy to 5 months postpartum
Differential Diagnosis ... orthopnea, PND, LE ... Avoid ARBs • ICD ... deteriorating on medical ... #treatment