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diagnosis hematology hemolytic causes extravascular workup anemias classification deficiency drugs ferritin iron macrocytic medications microcytic normocytic pharmacology testing
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
Hemolytic Anemias ... Signs of anemia ... Anemias (AIHAs) ... Intrinsic RBC Defects: Membrane ... #Anemias #Differential
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Hemolysis - Differential ... Diagnosis Algorithm ... Unstable Hgb - Membrane ... anemia • ... #Algorithm #Causes
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
anemia): ... thalassemias), Membrane ... #Hemolytic #Intravascular ... #Causes #differential ... diagnosis #hematology #anemia
Evaluation of Patients with Anemia Microcytic, Normocytic, Macrocytic, Hemolytic (Intravascular and Extravascular) #Diagnosis #Anemia #Workup #Macrocytic #Microcytic #Normocytic
Patients with Anemia ... Normocytic, Macrocytic, Hemolytic ... (Intravascular ... #Diagnosis #Anemia ... #Algorithm
Iron Deficiency Anemia - Differential Diagnosis Algorithm Labs: Ferritin, iron, transferrin, TIBC, TSAT, sTfR • Blood loss:
Iron Deficiency Anemia ... - Differential ... Diagnosis Algorithm ... ) hemolysis, Intensive ... Iron #Deficiency #Anemia
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Differential Diagnosis ... for Hemolytic Anemia ... thalassemias • Membrane ... IVIG infusion Intravascular ... #Anemia #Differential
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential ... Diagnosis Algorithm ... - Consider RBC membrane ... #Anemia #Differential
Drugs Implicated in Hemolytic Anemia • Hapten (Drug binding to RBC membrane): Penicillin, Cephalosporin, Tetracycline, Tolbutamide,
Implicated in Hemolytic ... Anemia • Hapten ... binding to RBC membrane ... #Anemia #differential ... #pharmacology #table
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