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differential management algorithm cryoglobulinemia renal thrombocytopenia treatment arteritis bleeding bloodcell bruising cerebritis child classification cns conditions crisis cryofibrinogenemia cryoglobulinemic cryoglobulins
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Causes of Thrombocytopenia ... - Differential Diagnosis ... HUS • DIC • Vasculitis ... #Algorithm #Causes ... #Hematology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... - Differential Diagnosis ... Rare • Drugs (e.g ... • Steroids • Vasculitis ... #Hematology
Renal involvement in 35% of mixed cryoglobulinemia vasculitis Associated with : • Absence of skin
cryoglobulinemia vasculitis ... min/1.73 m2 at diagnosis ... • Dialysis at diagnosis ... #Management #Rheumatology ... Cryoglobulinemic #Nephrology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential Diagnosis ... function test, ANA (e.g ... (CVID, WAS), (neurologic ... #Differential #Diagnosis ... #hematology
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Blood Cell (RBC) Morphology ... Chemotherapy (e.g ... #differential #diagnosis ... #hematology #microscopy ... #atlas #nomenclature
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY RED FLAGS - In all cases there are specific markers which
FLAGS - In all cases ... splenomegaly, abnormal neurology ... , back pain Haematology ... cell disease Rheumatology ... Peds #Pediatrics #Diagnosis
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
autoantibodies that will cause ... Lumbar Puncture, EEG ... Erythematosus #SLE #CNS #neurology ... #rheumatology # ... cerebritis #diagnosis
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... Labs/Diagnosis: ... tissue disorder (e.g ... classification #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Diagnosis Framework ... affects the skin, neurologic ... cognitive impairment, neurologic ... tract, and often causes ... #Rheumatology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
cryoglobulin (CG ... malignancies, vasculitis ... cryoglobulins • Negative causes ... #rheumatology # ... hematology
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