13 results
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
Signs / Symptoms / Complications ... Motor dysfunction: myoclonic ... incontinence, apraxia ... AlzheimersDisease #Dementia ... #pathophysiology
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect
Examples: Valproate, Carbamazepine, Lamotrigine
 • Mild anticholinergic effect -> Drowsiness
Dose-dependent tremor, ataxia ... dizziness, diplopia, ataxia ... Systemic effect -> Nausea ... #SideEffects #Pathophysiology ... #Psychiatry #Pharmacology
Lower Urinary Tract Infections: Complications
 - Infection damages the urinary tract epithelium causing fibroblast proliferation and
Tract Infections: Complications ... gain access to blood ... urea which may cause ... UrinaryTractInfection #LUTI #Pathophysiology ... #Complications
Widened Pulse Pressure - Differential Diagnosis and Pathophysiology

Pulse pressure is the difference between the systolic blood
Diagnosis and Pathophysiology ... Physiologic Causes ... Pathologic Causes ... • Sepsis Complications ... Differential #Diagnosis #Pathophysiology
Hyperuricemia: Pathogenesis and Complications

 - Hypercalcemia (due to diseases like Sarcoidosis and Hyperparathyroidism) -> Accumulation of
Pathogenesis and Complications ... acid from the blood ... Release of purine bases ... Hyperuricemia #Pathophysiology ... #Complications
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
impairment • HIV dementia ... Pathophysiology ... integrity of the blood-brain ... penetrance through the blood-brain ... motor slowing and ataxia
Causes of Myoclonus - Differential Diagnosis
LOCALIZATION:
 • Cortical: Focal/multifocal: Distal UL+ Face, Action/sensitive induced
 • Sub-Cortical:
Causes of Myoclonus ... degenerations, dementias ... acid-base, opioids, psychiatric ... MarcoMalaga97 #Myoclonus ... Differential #Diagnosis #Causes
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
hair follicles -> causes ... endothelium) & Decr blood ... Manifestations #pathophysiology ... signs #symptoms #complications
Thiamine Deficiency - Differential Diagnosis Framework and Clinical Manifestations

Causes of Thiamine Deficiency:
 • Poor intake:
	- Diets
Manifestations Causes ... increase venous blood ... Ophthalmoplegia - Ataxia ... vascular contraction, blood ... beriberi #nutrition #pathophysiology
Diabetic Foot: Pathogenesis and clinical findings
 • Polyol Pathway - Excess glucose enters Polyol pathway ->
Glycosylation - AGE cause ... Decreased insulin in blood ... the decreased blood ... #DiabeticFoot #pathophysiology ... #complications