6228 results
Management of Necrotizing Pancreatitis

Severe Pancreatitis
Pathophysiology
Diagnosis of Pancreatic Necrosis
Infected Necrosis
Complications of Severe Pancreatitis: 
1) Pancreatic Fistula
2) Disconnected
Pathophysiology Diagnosis ... of Pancreatic Necrosis ... Infected Necrosis ... Pancreatic Duct Syndrome ... Guidelines #Pancreatic #Necrosis
Calcific Uremic Arteriolopathy (calciphylaxis) - Hand photo and XRay
Based on this image, what is the likely
is the likely diagnosis ... calciphylaxis) - clinical syndrome ... calcification -> tissue necrosis ... Note necrotic lesions
Acute Kidney Injury - Classification
Prerenal:
 • Dehydration
 • Heart failure (a.k.a. cardiorenal syndrome)
 • Liver failure
a.k.a. cardiorenal syndrome ... a.k.a. hepatorenal syndrome ... Acute tubular necrosis ... Classification #diagnosis
Urinary Casts and Disease Associations
Hyaline - May be nonspecific; seen in normal individuals or during severe
acute tubular necrosis ... tuberculosis Fatty - Nephrotic ... syndrome ("Maltese ... Differential #Microscopy #Diagnosis
Streptococcal Toxic Shock Syndrome (STSS)
Complication of invasive GAS disease characterized by shock & MOF → occurs
Streptococcal Toxic Shock Syndrome ... 50% in nec fasc Diagnostic ... rash, soft tissue necrosis ... #Toxic #Shock #Syndrome ... treatment #management #diagnosis
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
cholestasis, no necrosis ... HELLP Syndrome ... unless massive necrosis ... Patchy/extensive necrosis ... #differential #diagnosis
Esophageal Necrosis
Etiology:
 - Ischemia and Gastric Outlet Obstruction with GERD may be inciting events
 - Associated
Esophageal Necrosis ... Stevens-Johnson syndrome ... Necrosis should ... retrosternal chest pain Diagnosis ... #diagnosis #management
Diagnosis of Cryoglobulinemia Vasculitis

1) Presence of cryoglobulin 
Circulating immunoglobulins that precipitate with cold temperature and dissolve
Diagnosis of Cryoglobulinemia ... Ulcers, distal necrosis ... Hyperviscosity syndrome ... Cryoglobulinemia #Vasculitis #Diagnosis
Causes of Hematuria - Differential Diagnosis
Renal:
 - Glomerular - IgA Nephropathy, Thin basement membrane, Alport syndrome,
- Differential Diagnosis ... membrane, Alport syndrome ... Ischemic - Papillary necrosis ... #Differential #Diagnosis
Common causes of Acute Kidney Injury AKI - Differential Diagnosis
HEMODYNAMIC
 • Cardiac failure: Impaired forward flow,
- Differential Diagnosis ... inhibitors, hepatorenal syndrome ... Tubular Injury/Necrosis ... #Differential #Diagnosis