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diagnosis differential causes rheumatology anemia bruising cryoglobulinemia cryoglobulins dermatitis erythema erythematosus gammopathy history lupus lymphomas lymphoproliferative mcv mgrs monoclonal nonhodgkin
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... Differential Diagnosis Algorithm ... Sequestration Disordered ... Rare • Drugs (e.g ... #Causes #Hematology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Lymphoproliferative Disorders ... lymphadenopathy more diffuse ... involvement, irregular pattern ... #Classification ... pathophysiology #Hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Differential Diagnosis Algorithm ... 80-100 fL) • Bleeding ... Chronic Disease (e.g ... #Anemia #MCV #Classification ... #Causes #Hematology
Helpful Clinical Features in Evaluating Bleeding Disorders Age of onset • Neonate - in 20% of haemophilias,
Drug history, e.g ... anticoagulants • Unusual pattern ... non-accidental injury Pattern ... #Bleeding #Disorders ... pediatrics #diagnosis #hematology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
immune system, leading ... hematological disorders ... (e.g. systemic ... diagnosis #types #classification ... #rheumatology #
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Skin Disease Classification ... . hematologic) ... • Endocrine disorders ... pneumonitis • Diffuse ... enteropathy, and diffuse
PALM RASHES Common features and patterns: 1. Color: o Red or erythematous: Common in inflammatory or allergic reactions. o Purple or purpuric:
Common features and patterns ... suggest vascular or hematologic ... depigmentation disorders ... o Peripheral patterns ... Drug Reactions: Diffuse
Monoclonal Gammopathy of Renal Significance (MGRS) MGRS • MGRS refers to kidney disease caused by nephrotoxic monoclonal immunoglobulins
or plasma cell disorder ... meet criteria for hematologic ... Why Does MGRS Matter ... or evolve into hematologic ... guide subtype classification
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