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diagnosis differential rheumatology causes classification dermatology erythematosus lupus sle alopecia ana antibodies antinuclear arthritis autoimmune bruising cerebritis cns cryofibrinogenemia cryoglobulinemia
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... Differential Diagnosis Algorithm ... Sequestration Disordered ... Rare • Drugs (e.g ... #Causes #Hematology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... Differential Diagnosis Algorithm ... Reactive: - Systemic ... Leukemia - History of Bleeding ... #Causes #Hematology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
significant • Pattern ... : The ANA patterns ... • Nucleolar: Diffuse ... Lymphoproliferative Disorders ... #rheumatology #
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Lymphoproliferative Disorders ... with lymphatic system ... lymphadenopathy more diffuse ... involvement, irregular pattern ... pathophysiology #Hematology
Causes of Splenomegaly - Differential Diagnosis Algorithm Infectious • Bacterial • Viral (EBV) • Parasitic • Fungal Congestive
Differential Diagnosis Algorithm ... Myeloproliferative disorders ... Inflammatory • Systemic ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
Helpful Clinical Features in Evaluating Bleeding Disorders Age of onset • Neonate - in 20% of haemophilias,
• Presence of systemic ... • Unusual pattern ... non-accidental injury Pattern ... #Bleeding #Disorders ... pediatrics #diagnosis #hematology
Allopecia - Differential Diagnosis Framework for Hair Loss Localized / Focal Hair Loss Pattern: • Scarring Alopecia:
Traction alopecia Diffuse ... Vitamin D levels Systemic ... Disorders: ... • Hormonal disorder ... Differential #Diagnosis #dermatology
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
Nail Disorders secondary ... to Systemic Diseases ... halt nail growth (e.g ... #Secondary #dermatology ... Differential #Diagnosis #Algorithm
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic ... Headache, Movement disorders ... , Seizure disorders ... inflammation, leading ... Lumbar Puncture, EEG
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
activate the immune system ... , leading to the ... hematological disorders ... (e.g. systemic ... classification #rheumatology
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