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diagnosis neurology lupus pharmacology treatment bradi bradycardia cerebritis cns crisis differential diuresis diuretics encephalopathy erythematosus excretion gravis hcq hydroxychloroquine hyperkalemia
Hydroxychloroquine Serum Measurement in SLE • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
Measurement in SLE ... (e.g. renal failure ... #Measurement #SLE ... #rheumatology # ... levels #lupus #management
Bradycardia - Differential Diagnosis Framework BRADI Mnemonic • BRASH/Hyperkalemia • Reduced oxygen/Glucose/Temp • ACS • Drugs •
Bradycardia • Renal ... Autoimmune: • SLE ... Failure of permanent pacemaker ... differential #diagnosis #causes ... #cardiology #BRADI
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... autoantibodies that will cause ... #CNS #neurology ... #rheumatology # ... cerebritis #diagnosis #management
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
Agents Regulating Renal ... irrigation • Management ... Kidney stones caused ... Postoperative abdominal distention ... Excretion #Diuresis #Nephrology
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
rheumatoid arthritis, SLE ... Serologic and EMG ... Myasthenia Crises ... Gravis #diagnosis #management ... #neurology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
heparinized tube) • ECG ... 15 suggests ↓ renal ... only if no clear cause ... and Elimination (see ... Treatment #potassium #nephrology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Immunosuppressive agents, Renal ... the underlying cause ... with AEDs until cause ... #diagnosis #management ... #neurology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... Hypocomplementemia • Can cause ... Distal (Type I) renal ... #Rheumatology # ... Diagnosis #Management
Scleroderma Renal Crisis (SRC) Clinical Presentation of Scleroderma Renal Crisis: 1) Acute kidney injury 2) Abrupt onset of hypertension 3)
of arteries Management ... • Refractory cases ... #Crisis #rheumatology ... #nephrology #diagnosis ... #management
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
hearing loss, nausea ... such as: • SLE ... Heart failure • Renal ... Polychondritis #rheumatology ... #diagnosis #management
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