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diagnosis oncology classification management blood cell enlarged essential et hodgkins leukemia lymphomas lymphoproliferative nonhodgkin pathophysiology plasmacytoma platelets solitary spleen splenomegaly
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
- Markers and Differential ... Diagnosis Algorithm ... Acute • Myloid ... , Auer rod • Lymphoid ... #hematology #Markers
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... Infectious: • Acute ... • Rheumatic disorders ... effect following treatment ... #Causes #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... Rebound effect from treatment ... Metastatic cancer, Lymphoma ... Inflammatory Conditions: Rheumatologic ... #hematology
Causes of Splenomegaly - Differential Diagnosis Algorithm Infectious • Bacterial • Viral (EBV) • Parasitic • Fungal Congestive
- Differential ... Malignant • Lymphoma ... Myeloproliferative disorders ... vera, essential thrombocytosis ... #Causes #Hematology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Disorders - Differential ... Diagnosis Algorithm ... Treated Like Acute ... pathophysiology #Hematology ... #algorithm
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
, APML, CLL Acute ... -> AML: Blast crises ... basophilia, and thrombocytosis ... PLT: Petechiae, bruising ... #Leukemia #Hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Autoimmune disorders ... hemolytic anemia • Pain ... (Inflammatory marker ... Treatment • Early ... classification #hematology
Essential Thrombocythemia (ET) ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
atypical chest pain ... hemoproliferative disorder ... • Treatment algorithms ... Thrombocythemia #ET #hematology ... diagnosis #management #hematology
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
presents with pain ... X-Ray Imaging: • Marked ... Biopsy: Solitary disorder ... Bone marrow Treatment ... Diagnosis #Workup #Hematology
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