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diagnosis causes renal classification glomerulonephritis hematuria syndrome vasculitis blood chronic ckd kidneydisease management mpgn nephrotic prs rpgn scd sicklecell syndromes
Causes of Proteinuria - Differential Diagnosis Algorithm Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Causes of Proteinuria ... • Drugs Glomerular ... • Membranoproliferative ... Minimal change disease ... #Nephrology #Differential
Sickle Cell Disease (SCD) Nephropathy • Cortical Manifestations - Main issue: Hemolysis-associated endothelial
Sickle Cell Disease ... alterations - Proteinuria ... - Glomerular ... pathology ... #SickleCell #Disease
Causes of Hematuria - Differential Diagnosis Algorithm Red blood cells on urine microscopy. Must exclude false positives
• Calculi Glomerular ... epithelial side of glomerular ... • Thin GBM disease ... • Pauci-immune disease ... nephrotic range) proteinuria
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
presenting with overt glomerular ... proteinuria. ... impairment), heart disease ... diagnosis cluster, the diseases ... #Algorithm #differential
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
Membranoproliferative ... RBC casts, +/- proteinuria ... formation along glomerular ... (Dense deposit disease ... Glomerulonephritis #MPGN #nephrology
Rapidly Progressive Glomerulonephritis (RPGN) - Loss of kidney function over a short period of tirne
with evidence of glomerular ... disease (hematuria ... , proteinuria) ... immune deposits in glomeruli ... post-infectious GN Anti-Glomerular
Causes of Chronic Kidney Disease - Differential Diagnosis Algorithm Decreased kidney function (eGFR < 60 ml/min/1.73 m2)
Chronic Kidney Disease ... of Renovascular disease ... Medullary cystic disease ... Atherosclerosis Glomerular ... (Proteinuria)
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
Peripheral edema, Disease-specific ... vasculitis, Behcet disease ... sclerosis • Anti-Glomerular ... Goodpasture's Disease ... • Urinalysis (proteinuria
Hematuria - Differential Diagnosis Framework Gross Hematuria: Red/Dark urine • 1ml blood/liter urine can induce color change
or dipstick) Glomerular ... • Causes of Glomerular ... basement membrane disease ... Brown urine - Proteinuria ... disease Renal
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
life-threatening diseases ... • Renal: (AKI, proteinuria ... Inflammatory eye disease ... casts, low grade proteinuria ... hypercellular glomeruli
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