13 results
Inherited Qualitative Platelet Defects
Bernard-Soulier Syndrome
 • Defect of adhesion due to a lack of GP Ib/IX/V
receptor] • Thrombocytopenia ... MYH9-Related Disorder ... #Defects #comparison ... #table #differential ... #diagnosis #hematology
Thrombocytopenia - Differential Diagnosis Algorithm

Decreased production:
 • Bone marrow suppression
 • Bone marrow failure
 • Bone
Thrombocytopenia ... Diagnosis Algorithm ... Connective tissue disorders ... Diagnosis #Algorithm ... #hematology #platelets
Platelet disorders and Aggregometry
Glanzmann Thrombasthenia
 • Defective aggregation to all agonists except ristocetin
 • Normal platelet,
Platelet disorders ... Gplb receptor • Thrombcytopenia ... #disorders #hematology ... #hemepath #differential ... #diagnosis #Aggregometry
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
- Markers and Differential ... Diagnosis Algorithm ... #hematology #Markers ... #Differential # ... Diagnosis #Algorithm
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
- Differential ... Diagnosis Algorithm ... • Rheumatic disorders ... following EtOH induced thrombocytopenia ... Diagnosis #Algorithm
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
- Elevated Platelet ... Diagnosis Algorithm ... blood loss, Acute hemolysis ... #Platelets #Differential ... #Diagnosis #Algorithm
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Diagnosis Algorithm ... with or without platelet ... Schistocytes, thrombocytopenia ... Consider RBC membrane disorder ... #Diagnosis #Algorithm
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Diagnosis Algorithm ... Thrombocytopenia ... Platelet Function ... #Diagnosis #Algorithm ... #Causes #Hematology
Causes of Splenomegaly - Differential Diagnosis Algorithm
Infectious
 • Bacterial
 • Viral (EBV)
 • Parasitic
 • Fungal
Congestive
Diagnosis Algorithm ... Myeloproliferative disorders ... vera, essential thrombocytosis ... Serum Sickness Hemolytic ... #Diagnosis #Algorithm
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Diagnosis Framework ... inflammation • Thrombocytopenia ... DIC/TTP/HUS - Hemolytic ... #Diagnosis #hematology