30 results
Metformin Pharmacology Summary
Mechanisms of Action:
 • Suppresses gluconeogenesis by the liver
 • Increases insulin-mediated glucose utilization
Metformin Pharmacology ... agent • Does not cause ... #Metformin #Pharmacology ... #Summary #DM2 # ... diabetes #endocrinology
Pathophysiology of Diabetic Ketoacidosis (DKA) and Hyperglycemic Hyperosmolar Syndrome (HHS)
Absolute Insulin deficit:
 - Type I DM:
Pathophysiology ... Hyperglycemic Hyperosmolar Syndrome ... deficit: - Type I DM ... #dka #hhs #pathophysiology ... #comparison #endocrinology
Selective Serotonin Reuptake Inhibitors: Mechanisms and Side Effects
 • Serotonin Syndrome:
   - Autonomic Hyperactivity:
• Serotonin Syndrome ... SSRI Withdrawal Syndrome ... Dizziness - Nausea ... Serotonin #Inhibitors #Pathophysiology ... #Pharmacology #
GLP-1 Receptor Agonists - Pharmacology Summary
Mechanisms of Action: Stimulate glucose-dependent insulin release from the pancreas (GLP-1
Receptor Agonists - Pharmacology ... not definitively cause ... Receptor #Agonists #Pharmacology ... #Summary #DM2 # ... diabetes #endocrinology
Secondary Causes of Hypertension - Differential Diagnosis Algorithm
Hypertension - BP > 140/90 (>130/80 for DM)
Hypertensive urgency
90 (>130/80 for DM ... end-organ damage or DM ... • Nephritic syndrome ... Excess: • Conn's syndrome ... HTN #Secondary #Nephrology
DPP-4 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits DPP-4 (dipeptidyl peptidase 4), which normally inactivates GLP-1
4 Inhibitors - Pharmacology ... not definitively cause ... DPP4 #Inhibitors #Pharmacology ... #Summary #DM2 # ... diabetes #endocrinology
Serotonin-Norepinephrine Reuptake Inhibitors(SNRIs): Mechanisms and Side Effects

Withdrawal: Dizziness, Diarrhea, Insomnia, Nausea, Vomiting
Serotonin Syndrome - Potentially Life
Diarrhea, Insomnia, Nausea ... Vomiting Serotonin Syndrome ... gain Incr NE: Nausea ... SerotoninNorepinephrine #Inhibitors #Pathophysiology ... #Pharmacology #
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
share the same pathophysiology ... • Other rare causes ... Carpal Tunnel Syndrome ... signs #symptoms #endocrinology ... #pathophysiology
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect
Examples: Valproate, Carbamazepine, Lamotrigine
 • Mild anticholinergic effect -> Drowsiness
Stevens-Johnson Syndrome ... , asthenia • Neurologic ... Systemic effect -> Nausea ... #SideEffects #Pathophysiology ... #Psychiatry #Pharmacology
SGLT2 Inhibitors 
SGLT2 inhibitors are the newest class of anti-diabetic medications, with the first one (Canagliflozin)
kidney), which causes ... SGLT2 #Inhibitors #Pharmacology ... #Medications #DM2 ... #Diabetes #Endocrinology