17 results
Cyanide Toxicity 
Treatment:
1) Hydroxocobalamin + Cyanide = Cyanocobalamin (nontoxic) 
   or 
2) Amyl nitrite
Cyanide Toxicity ... Amyl nitrite - causes ... #Cyanide #Toxicity ... #Toxicology #Pathophysiology ... #Management #Treatment
Gamma hydroxybutyrate (GHB) - Toxicology

Clinical presentation
 - Symptoms of GHB toxicity include: short term anterograde amnesia,
hydroxybutyrate (GHB) - Toxicology ... of GHB toxicity ... Hydroxybutyrate #GHB #Toxicology ... #Toxicity #Diagnosis ... #Management #Pharmacology
Salicylate Toxicity - Diagnosis and Management

Clinical Findings
Pathophysiology
Workup
Treatment

By Stacy Marshall, MD

#Salicylate #Toxicity #Diagnosis #Management #Toxicology #Aspirin #Treatment
Salicylate Toxicity ... Diagnosis and Management ... Clinical Findings Pathophysiology ... Workup Treatment ... #Toxicology #Aspirin
Salicylate Toxicity - Diagnosis and Management

Consider if:
1) Patient is hot and altered
2) You see tachypnea with
Salicylate Toxicity ... no respiratory cause ... ingestion/exposure Symptoms ... Salicylate #Aspirin #Toxicity ... #Toxicology #diagnosis
Metformin Associated Lactic Acidosis (MALA) 

Pathophysiology of MALA
 - Metformin interferes with the activity of the
Acidosis (MALA) Pathophysiology ... also includes symptoms ... LacticAcidosis #Toxicity ... #Toxicology #Diagnosis ... #Management
 Acute Iron Poisoning

There are five classically described phases of toxicity:
Gastrointestinal phase (~6 hours post-ingestion)
 -
described phases of toxicity ... Abdominal pain, nausea ... post-ingestion) - Symptom ... #Toxicology #Diagnosis ... #Management #Ferrous
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms ... • Immunologic Workup ... constitutional symptoms ... • Immunologic Workup ... Lupusreference #druginduced
Clozapine Toxicology
Clozapine is an atypical antipsychotic most often reserved for use in patients who have treatment-resistant
Clozapine Toxicology ... effect on negative symptoms ... Clozapine is known to cause ... #Toxicity #Diagnosis ... #Pharmacology
Histamine Fish Toxicity - Inadequate refrigeration increases enzyme from bacteria on fish 
Clinical 
• Skin flushing,
Histamine Fish Toxicity ... Oral burning, nausea ... palpitations • Symptoms ... eating fish Management ... #Toxicology #Diagnosis
Digoxin Pharmacology and Pathophysiology
1) Na/K ATPase Pump - Digoxin works by directly binding to and inhibiting
Digoxin Pharmacology ... and Pathophysiology ... Pump - Digoxin works ... intracellular calcium causes ... #Pathophysiology