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diagnosis management differential hematology treatment aids hemophagocytic hiv hlh lymphohistiocytosis algorithm anatomy associated cerebritis coagulation dementia dic diffuse disorder disseminated
Type IV Hypersensitivity: Pathogenesis and clinical findings Definition: Unique because it is entirely T-Cell mediated; exposure to
causes development ... -> Particular CD4 ... + Th cells recognize ... harmful -> Th Cells ... #Immunology #pathophysiology
Bell's Palsy Bell’s Palsy is a damage, acute weakness, or paralysis of the Facial nerve (7th CN),
Facial nerve (7th CN ... an identifiable cause ... The cause is unknown ... #Palsy #neurology ... #anatomy #pathophysiology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... • Acne • Allergy ... Lymphocytic Leukemia (CBC ... Reed-Sternberg Cells ... #Hematology #Oncology
CNS Infection in HIV / AIDS - Differential Diagnosis Framework Principles of HIV-Associated CNS Opportunistic Infections: •
less than 200 cells ... status, and focal neurologic ... Demyelinating disease caused ... confusion, and focal neurologic ... InfectiousDiseases #Neurology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Disease, PRES Pathophysiology ... autoantibodies that will cause ... Erythematosus #SLE #CNS ... #neurology #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... →Activation of CD8 ... T cells (IFN-y) ... Drugs, Unknown cause ... treatment #summary #rheumatology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
protein C and S Pathophysiology ... Thromboembolism (7%) • CNS ... Schistocytes, helmet cells ... Treat primary cause ... Coagulation #diagnosis #causes
HIV-Associated Neurocognitive Disorder (HAND) Definition: HIV-Associated Neurocognitive disorders categories: • Asymptomatic neurocognitive impairment • Mild neurocognitive impairment • HIV dementia Pathophysiology: HIV frequently
HIV dementia Pathophysiology ... and infects the CNS ... in the CNS ○ ... HIV and with low CD4 ... dementia #AIDS #Neurology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... /aggregate) of CD4 ... nervous system (CNS ... • 8%-27% for CNS ... Sjogrens #Syndrome #Rheumatology
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... that results in CNS ... Pleocytosis > 100 cells ... • Infectious causes ... diagnosis #management #neurology
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