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HepatoRenal Syndrome - Pathophysiology

Dr. Edgar V. Lerma @edgarvlermamd - Nephrology Secrets https://amzn.to/34t5DgJ

#HRS #HepatoRenal #Syndrome #Pathophysiology #Diagnosis
HepatoRenal Syndrome ... - Pathophysiology ... edgarvlermamd - Nephrology ... #Diagnosis #Nephrology ... #AKI
Causes of HyperKalemia - Differential Diagnosis
Increased extracellular K+:
 • Tissue injury
 • Hemolysis
 • Rhabdomyolysis
 •
- Differential ... • Tumor lysis syndrome ... Elimination: • AKI ... blockers - MCW Nephrology ... #Differential #
Hypokalemia - Differential Diagnosis Algorithm

Transcellular Shift:
 • Alkalosis
 • ↑ beta-2 adrenergic simulation 
 • Erythropoiesis
Hypokalemia - Differential ... • G-CSF • Hypokalemic ... • Refeeding syndrome ... #Differential # ... Diagnosis #Algorithm #nephrology
Causes of Hyponatremia - Differential Diagnosis Algorithm
Syndrome of Inappropriate ADH - Euvolemic; no physiologic stimulus to
Hyponatremia - Differential ... Pain/Post-op • Neurologic ... Malignancy True hypovolemia ... • Reduced GFR, AKI ... #Hyponatremia #Nephrology
Causes of Hyponatremia - Differential Diagnosis Algorithm
Syndrome of Inappropriate ADH - Euvolemic; no physiologic stimulus to
Hyponatremia - Differential ... Pain/Post-op • Neurologic ... Malignancy True hypovolemia ... • Reduced GFR, AKI ... #Hyponatremia #Nephrology
Acute Kidney Injury (AKI) - Differential Diagnosis Framework

PRE-Renal AKI:
 • Hypovolemia
 • Congestion
 • Medications
 •
Kidney Injury (AKI ... ) - Differential ... : • Hypovolemia ... Kidney #Injury #Differential ... #Diagnosis #nephrology
Acute Kidney Injury (AKI) - Differential Diagnosis Framework
Pre-Renal:
 • Hypovolemia, Cardiorenal, Distributive Shock, HRS, Hypercalcemia, Renal
Kidney Injury (AKI ... ) - Differential ... Pre-Renal: • Hypovolemia ... Abdominal Compartment Syndrome ... #Diagnosis #nephrology
General approach to AKI - Checklist

Urine electrolytes & FENa - Previously, it was believed that urine
General approach to AKI ... believed that urine sodium ... FENa) could help differentiate ... @PulmCrit #AKI ... AcuteKidneyInjury #Nephrology
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Pathophysiology ... thiazide-sensitive sodium-chloride ... H+ secretion → Hypokalemia ... #Pathophysiology ... #nephrology #diagnosis
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Hypokalemia - Differential ... , Gitelman syndrom ... @priti899 #Hypokalemia ... #Differential # ... potassium #low #nephrology