21 results
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Arthralgia/arthritis, Skin ... rash ± odynophagia ... solid cancers • Systemic ... Prunelle Getten #AdultOnset ... #rheumatology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features of Systemic ... Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... erythematosus #signs #symptoms ... #diagnosis #rheumatology
Adult-Onset Still's Disease (AOSD)
Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
maculopapular rash ... episode (30%) Systemic ... synovitis (40%) Treatment ... BrighamChiefs #AdultOnset ... Disease #AOSD #rheumatology
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
weakness, less systemic ... symptoms, and less ... can present with rash ... after 2 years of treatment ... Myositis #diagnosis #rheumatology
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Disorders Testing Algorithm ... workup for specific symptoms ... glucocorticoid treatment ... (eg, skin or esophageal ... Differential #diagnosis #hematology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
site in lymphatic system ... with lymphatic system ... pattern of spread, B symptoms ... Classification #pathophysiology ... #Hematology #Diagnosis
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
sudden onset of a rash ... - Rash: multiple ... symptoms by days ... , breast CA - Hematologic ... Treatment: - Systemic
Secondary Syphilis Rash
Secondary syphilis is the most contagious of all the stages of this disease, and
characterized by a systemic ... Skin rash and malaise ... The signs and symptoms ... with or without treatment ... , but without treatment
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
Eosinophilia and Systemic ... Symptoms (DRESS ... rash in association ... Symptoms: • The ... disease: symptomatic treatment
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
Still's Disease Systemic ... the chest/trunk Symptoms ... maculopapular skin ... Treatment - Mild ... AOSD #diagnosis #rheumatology