22 results
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... old, ~10,000 new cases ... transformation to acute leukemia ... only curative treatment ... #hematology #oncology
Inherited Non-hemolytic Disorders of Hyperbilirubinemia 

== Disorders of Conjugation ==
Gilbert Syndrome:
 • 5-10% of the population
Conjugation == Gilbert Syndrome ... hyperbilirubinemia syndrome ... examination; nonspecific symptoms ... and stress may cause ... #hepatology #diagnosis
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
rapid onset of symptoms ... -> AML: Blast crises ... develop leukostasis syndrome ... • Tumor lysis syndrome ... #Hematology #Oncology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... Dehydration • Symptoms ... : • Pathophysiology ... diagnosis #management #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
with no early symptoms ... microglobulin Treatment ... • Richter’s Syndrome ... • Sezary syndrome ... workup #oncology #hematology
Irritable Bowel Syndrome (IBS) - Management
Global IBS Symptoms:
  - Limited trial low FODMAP diet
Irritable Bowel Syndrome ... Management Global IBS Symptoms ... Rifaximin- up to 3 courses ... Gastroenterology and Hepatology ... gastroenterology #treatment
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Episcleritis Signs and Symptoms ... development of skin symptoms ... Causes: - Idiopathic ... , breast CA - Hematologic ... Treatment: - Systemic
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
pattern of spread, B symptoms ... Responsive to Treatment ... Treated Like Acute Leukemias ... Classification #pathophysiology ... #Hematology #Diagnosis
Irritable Bowel Syndrome (IBS) - Diagnosis and Management Summary
Diagnosis:
 • Use a positive diagnostic strategy with
Irritable Bowel Syndrome ... for diagnosis Treatment ... Rifaximin- up to 3 courses ... Gastroenterology and Hepatology ... Irritable #Bowel #Syndrome
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
without other cause ... ARDS to explain symptoms ... : 33% • Treatment ... : No • Treatment ... Transfusion #Reactions #hematology