34 results
Pathophysiology, Signs and Symptoms of Hemolytic Anemia

#Pathophysiology #Hemolytic #Anemia #hematology #diagnosis #signs #symptoms
Signs and Symptoms ... of Hemolytic Anemia ... #Hemolytic #Anemia ... #hematology #diagnosis ... #signs #symptoms
Hemolytic Anemias - Differential Diagnosis Algorithm

Signs of anemia and hemolysis:
 • ↓ Haptoglobin
 • ↑ LDH
Hemolytic Anemias ... Diagnosis Algorithm Signs ... of anemia and hemolysis ... Hypersplenism, Infection ... Diagnosis #Algorithm #hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cryoglobulins (Vasculitic ... - Due to Viral infection ... of anemia include ... anemia • Cold ... #anemia #hematology
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations
Risk Factors:
 - Unclear environmental triggers (may be viral, not
yrs old; F>M Signs ... /Symptoms: - Fever ... - Normocytic Anemia ... Temporal #Arteritis #Pathophysiology ... #Symptoms #Vasculitis
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... cardiac valve, vasculitis ... inclusions - If infection ... #Anemia #Differential ... Algorithm #workup #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... blood loss, Acute hemolysis ... , deficiency anemia ... Rheumatologic, Vasculitides ... : Chronic infections
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
DIC/TTP/HUS - Hemolytic ... anemia - Splenomegaly ... SLE) - Viral infections ... APLS • Acute Infectious ... Differential #Diagnosis #hematology
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Aplastic Anemia ... Illness Script Signs ... and symptoms: ... • Recurrent infections ... management #treatment #hematology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Butterfly rash, Vasculitis ... ) Blood (75%): Anemia ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework

LDH is a cytoplasmic enzyme present in tissues throughout
anemia, PNH, immune ... - Pernicious anemia ... • Toxins • Infection ... tumor burden) Vasculitis ... associated with any symptoms