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differential hematology causes workup atlas classification mcv morphology rbc testing alkaline alkphos alp approach arthritis astalt bilirubin bloodcell chemistry deficiency
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
Algorithmic Approach ... Diagnosis Framework ... inflammation) • Iron ... Non-megaloblastic: Liver ... #hematology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
- Differential Diagnosis ... Algorithm Decreased ... • Early Iron ... #Algorithm #Causes ... #Hematology
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
• Microcytic - Iron-deficiency ... spherocytosis, Hemolytic ... Schistocytes - Hemolytic ... Morphology #Atlas #key #diagnosis ... #differential #hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
- Differential Diagnosis ... Algorithm Low ... Volume (<80 fL) • Iron ... • Bleeding • Hemolysis ... #Hematology
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
, Thalassemia, Iron ... Microangiopathic Hemolytic ... elliptocytosis, Severe iron ... #differential #diagnosis ... #hematology #microscopy
Iron Deficiency Anemia - Differential Diagnosis Algorithm Labs: Ferritin, iron, transferrin, TIBC, TSAT, sTfR • Blood loss:
Anemia - Differential ... Diagnosis Algorithm ... extravascular) hemolysis ... #Deficiency #Anemia ... #hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
- Differential Diagnosis ... Algorithm Blood ... MCH, MCHC, Serum Iron ... Disorder • RBC Metabolism ... #Hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential Diagnosis ... Algorithm • Sickle ... defects, Glutathione metabolism ... #Diagnosis #Algorithm
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... acute blood loss, hemolysis ... substrate (e.g. iron ... #Algorithm #Diagnosis ... #Workup #Hematology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Diagnosis Framework ... Defects, Drugs, Liver ... Defects: Sickle cell anemia ... Hypophostphatemia Laboratory ... #hematology
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