11 results
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
HIV / AIDS - Differential ... present in 15% of cases ... Antimicrobial treatment ... Demyelinating disease caused ... opportunistic #InfectiousDiseases
Amebiasis - Naegleria fowleri - Life Cycle
1) Cysts
2) Trophozoite
3) Flagellated Form
4) Promitosis
→ Water-related activities such as
Trophozoites in CSF ... Naegleria #fowleri #LifeCycle ... #diagnosis #pathophysiology ... #infectiousdiseases ... #cdc #parasite
Trypanosomiasis - Trypanosoma cruzi Life Cycle
1) Triatomine bug takes a blood meal (passes metacyclic trypomastigotes in
a blood meal (passes ... TrypanosomaCruzi #Tcruzi #LifeCycle ... #diagnosis #pathophysiology ... #infectiousdiseases ... #cdc #parasite
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
dementia Pathophysiology ... and infects the CNS ... : • Increased CSF ... and with low CD4 ... Treatment: • HAART
CSF Penetration of Antimicrobials

Despite the poor CSF penetration, beta-lactams have the most research documenting successful treatment
documenting successful treatment ... other antibiotic classes ... FDA-approved for UTI treatment ... Antimicrobials #InfectiousDiseases ... #Pharmacology
Angiostrongyliasis - Angiostrongylus costaricensis Life Cycle
1) Eggs hatch in the ileum, and first-stage larvae are passed
eggs in tissues causes ... costaricensis #LifeCycle ... #diagnosis #pathophysiology ... #infectiousdiseases ... #cdc #parasite
Lung Infections in HIV - Differential Diagnosis Framework

Disease by CD4 Count:
Any CD4 Count:
 • Mycobacterium tuberculosis,
Infections in HIV ... Lymphadenopathy, CNS ... factor • May cause ... PARASITIC PNEUMONIAS ... differential #diagnosis #infectiousdiseases
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
• Most common cause ... Lung Abscess Pathophysiology ... Diagnosis: • CBC ... Coccidioides • Parasite ... #differential #causes
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... that results in CNS ... • Infectious causes ... simplex virus, HIV ... Transverse Myelitis Treatment
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... TYPE IV RTA, TYPE ... /aggregate) of CD4 ... Adenocarcinoma Treatment ... lubricants • Pharmacologic