13 results
Stroke and bleeding risk stratification with the CHADS2-VASc and HAS-BLED schemas

#Diagnosis #Hematology #CHADS2 #CHADS2VASc #HASBLED #Comparison
Stroke and bleeding risk ... #Diagnosis #Hematology ... CHADS2VASc #HASBLED #Comparison ... #Score #Risk #Stroke ... #Bleed #Anticoagulation
Coagulation Cascade and Anticoagulant Sites of Action

- Amy Chung, MD, MSc https://twitter.com/AmyChung

#AntiCoagulation #Cascade #Anticoagulants #Medications #Pharmacology
twitter.com/AmyChung #AntiCoagulation ... #Medications #Pharmacology ... #Pathophysiology ... Mechanisms #DOAC #Hematology
CHA2DS2VASc vs HAS-BLED scores for stroke risk and bleed risk on anticoagulation

C	Congestive Heart Failure	1

H	Hypertension	1

A2	Age >75	2

D	Diabetes Mellitus	1

S2	Stroke,
on anticoagulation ... Elderly (>65) 1 D Drugs ... CHADS2VASc #HASBLED #Comparison ... #Bleed #Anticoagulation ... AFib #Diagnosis #Hematology
Managing warfarin INR

Warfarin dosage must be individualized according to the patient's response to the drug, and
response to the drug ... Over-anticoagulation ... management #algorithm #pharmacology ... decisionaid #cardiology #hematology
Drug Induced Systemic Lupus Erythematosus
> 100 drugs have been associated with drug-induced SLE
High risk (>5%):
 •
Drug Induced Systemic ... Lupus Erythematosus ... SLE #Systemic #Lupus ... #pharmacology # ... #diagnosis #rheumatology
Myositis and Myopathies
Polymyositis 
 • Progressive, symmetric muscle weakness 
 • Elevated CK, +Anti-Jo, +Anti-Mi2
Dermatomyositis
HIV viral load Drug-induced ... Anti-retrovirals, Gemcitabine Lupus ... uncommon 5-15% of lupus ... differential #diagnosis #comparison ... #rheumatology
Hydroxychloroquine - Risks and Benefits in Lupus
Benefits:
↓ Disease activity, ↓ Flare, ↓ Damage, ↓ Corticosteroid dose,
Hydroxychloroquine - Risks ... and Benefits in Lupus ... #Benefits #Lupus ... #pharmacology # ... #sideeffects #rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Drug Induced Lupus ... vs SLE Drug Induced ... cases, drug-dependent ... #sle #comparison ... #table #rheumatology
Treatment algorithm for VTE in Malignancy

(A) Suggested treatment algorithm for symptomatic and incidental DVT or PE
patients at high risk ... §Assess drug-drug ... also balance the risk ... Cancer #Algorithm #Anticoagulation ... #Management #Hematology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
transfused patientsl • Risk ... blood donor • Pathophysiology ... transfused patients • Risk ... Transfusion #Reactions #hematology ... #diagnosis #comparison