15 results
Summary of Coagulation Deficiencies
Inherited:
 • Hemophilia A - Deficiency of Factor VIII
 • Hemophilia B -
malnutrition, Antibiotics ... RA, SLE), Post-partum ... Summary #table #comparison ... #diagnosis #hematology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
vs SLE Drug Induced ... Usual therapeutic management ... #comparison #table ... #rheumatology # ... diagnosis #management
Hydroxychloroquine Serum Measurement in SLE
 • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
Measurement in SLE ... #Measurement #SLE ... #rheumatology # ... pharmacology #levels ... #lupus #management
Managing warfarin INR

Warfarin dosage must be individualized according to the patient's response to the drug, and
response to the drug ... #management #algorithm ... #pharmacology # ... decisionaid #cardiology #hematology
Oral Antibiotics for Acne - Indicated for Moderate-to-Severe Acne 
First-Line Drug Class: Tetracyclines 

In the last
Oral Antibiotics ... Acne First-Line Drug ... talk about oral antibiotics ... #Pharmacology # ... Management #Dermatology
Flutycosine - Antibiotics Class Overview
 - 
Mechanism: 5-FC interferes with DNA and protein synthesis.  Only
Flutycosine - Antibiotics ... B for initial management ... adverse effects = Hematologic ... - Drug levels ... #Pharmacology #Antibiotics
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... Disease, PRES Pathophysiology ... Erythematosus #SLE ... CNS #neurology #rheumatology ... cerebritis #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... Autoimmune diseases: SLE ... immune deficiency, Drugs ... Lymphohistiocytosis #diagnosis #management ... treatment #summary #rheumatology
Drug Induced Systemic Lupus Erythematosus
> 100 drugs have been associated with drug-induced SLE
High risk (>5%):
 •
Drug Induced Systemic ... SLE High risk ... #DrugInduced #SLE ... #pharmacology # ... differential #diagnosis #rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
erythematosus [SLE ... ) • Sepsis • Drug-induced ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology