14 results
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
APML, CLL Acute ... count ↑ PLT • ↑ PBS ... ) CLL Symptoms: ... mosquito bites CLL ... #Hematology #Oncology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
incompetent • CLL ... Lymphocytosis on CBC ... leukemia #CLL ... diagnosis #workup #oncology ... #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
transformation to acute leukemia ... Allogeneic stem cell ... Myelodysplastic #Syndrome #MDS ... #treatment #hematology ... #oncology
Diffuse large B cell lymphoma (DLBCL) - Management and Treatment Algorithm

By Matthew Ho, MD PhD @MatthewHoMD

#Diffuse
Diffuse large B cell ... lymphoma (DLBCL) - Management ... By Matthew Ho, MD ... Treatment #Algorithm #oncology ... #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
(CLL) - Summary ... Vmphocytosis on routine CBC ... Lauren Banaszak, MD ... #oncology #hematology ... hemeonc #diagnosis #management
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Liver Disease, MDS ... Burr Cell RBC (Echinocyte ... Bite Cell RBC: G6PD ... differential #diagnosis #hematology ... #microscopy #atlas
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Consider stem cell ... Can progress to MDS ... or acute leukemia ... Anemia #diagnosis #management ... #treatment #hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
virus (EBV) • Leukemia ... • ↓ WBC • ↓ ... Aplastic #Anemia #oncology ... #hematology #diagnosis ... #management
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
• Induce blast cell ... if high risk if WBC ... QD until normal WBC ... APML #diagnosis #management ... #hematology #oncology
Consensus Indications for Irradiated RBC Transfusions:

Cellular blood components are irradiated for the prevention of TA-GVHD. Transfused
for Irradiated RBC ... Hematopoietic stem cell ... Daniela Hermelin, MD ... #Indications #Hematology ... #BloodBank #Management