1006 results
Systemic Sclerosis (Scleroderma)
Limited - CREST:
 • Calcinosis
 • Raynaud phenomenon
 • Esophageal dysmotility
 • Sclerodactyly
 •
Calcinosis • Raynaud phenomenon ... diagnosis #signs #symptoms
CREST Syndrome: Pathogenesis and Clinical Findings

CALCINOSIS (BB-sized, hard nodules in fingers)
RAYNAUD'S Phenomenon
ESOPHAGEAL DYSMOTILITY
SCLERODACTYLY (thickening and tightening
fingers) RAYNAUD'S Phenomenon ... Diagnosis #Signs #Symptoms
Primary Biliary Cirrhosis - Diagnosis Algorithm
Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort
Signs: Jaundice, Xanthelasmata, Hepatomegaly
Associated history:
Diagnosis Algorithm Symptoms ... Associated history: Symptoms ... mouth, Raynaud's phenomenon
Raynaud’s Phenomenon: Pathogenesis and clinical findings
 • Finger pulp atrophy
 • Tissue ischemia/infarction -> Digital ulcerations
Raynaud’s Phenomenon ... #Raynauds #Phenomenon ... pathophysiology #signs #symptoms
Systemic Lupus Erythematosus (SLE) - Typical Signs/Symptoms
Alopecia, Fever, Malar rash, Photosensitivity, Adenopathies, Lupus pneumonia, Pleurisy, Pancreatitis,
Typical Signs/Symptoms ... enteritis, Raynaud's phenomenon ... Erythematosus #SLE #Signs #Symptoms
Hashitoxicosis

‘Leakage’ symptoms of active Hashimoto’s disease

- Hashitoxicosis (Htx) can occur during the initial hyperthyroid stage in
Hashitoxicosis ‘Leakage’ symptoms ... ‘Leakage’ symptoms ... in ‘Leakage’ phenomenon
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
rare) Raynaud's phenomenon ... erythematosus #signs #symptoms
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Vasculitis, Raynaud's Phenomenon ... diagnosis #signs #symptoms
Fibromyalgia Symptoms
Cardinal Features:
 • Sleep disturbances: Insomnia, Frequent awakening, Non-restoring sleep
 • Pain: Generalized (head-to-toes), Described
Fibromyalgia Symptoms ... • Psychiatric symptoms ... including Raynaud phenomenon ... #Fibromyalgia #Symptoms
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
• Uhthoff’s phenomena ... defect SIGNS/SYMPTOMS ... Signs and symptoms ... Functionally disabling symptoms ... /or cerebellar symptoms