9 results
Who to test for BRCA 1/2?
Female Breast Cancer:
 • ≤ 45-50 years at diagnosis
 • Triple
test for BRCA 1/ ... 45-50 years at diagnosis ... relative meeting criteria ... #indications #oncology ... #screening #diagnosis
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
• Leukocytosis Diagnosis ... - Yamaguchi criteria ... 5 of the below criteria ... should be major: 1. ... #rheumatology #
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
ATRA treatment Pathophysiology ... damage • Induce blast ... symptoms, or> 1 ... #management #hematology ... #oncology
Evaluation of suspected incomplete Kawasaki Disease

1. AHA consensus recommendations
2. Infants ≤6 months old on day ≥7
Kawasaki Disease 1. ... Infants ≤6 months old ... Can treat before ... purposes of this algorithm ... #Diagnosis #Peds
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework

Heat Cramps:
 • Muscle pain or spasm -
- Differential Diagnosis ... on the skin • Areas ... Collapse: • Pathophysiology ... heat stress • Criteria ... Multi-system illness: 1.
CPPD vs Gout

== CPPD == 

Think About CPPD When:
 • Self-limited synovitis after surgery/trauma (> 65
trauma (> 65 years old ... disease states Pathophysiology ... Intermittent Gout: • Great ... Gout #Comparison #rheumatology ... #Diagnosis
Conduct Disorder (CD): Pathogenesis and clinical findings
 - Must have >3 symptoms present in the past
months, with >1 ... , criteria must ... in childhood (> 1 ... BehavioralDisorder #Pathophysiology ... #diagnosis #symptoms
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
dysfunction. 1. ... Pathophysiology ... Diagnostic Criteria ... of 8 HLH-2004 criteria ... • Treat underlying
Oppositional Defiant Disorder (ODD): Pathogenesis and clinical findings
 - Must have >4 symptoms for >6 months,
is considered mild ... present in only 1 ... BehavioralDisorder #Pathophysiology ... #diagnosis #symptoms ... signs #psychiatry #criteria