28 results
Hemophagocytic Lymphohistiocytosis (HLH)
Clinical Features: Fever, Splenomegaly, Hepatomegaly, Lymphadenopathy, Confusion
Classic lab findings in HLH: ↑↑ ferritin, Anemia,
ferritin, Anemia, Thrombocytopenia ... activity, ↑ soluble IL ... -2 receptor Diagnostic ... ): Molecular diagnosis ... #hematology #criteria
4T Score for Heparin-Induced Thrombocytopenia

Interpretation of the 4T score:
0-3 points:  Low probability (<<1%)
  -
Heparin-Induced Thrombocytopenia ... probability (<<1% ... HeparinInduced #Thrombocytopenia ... #Diagnosis #Criteria ... #Hematology
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Thrombocytopenia ... the critically ill ... coagulation defects. 1) ... Obstetrics #OBGyn #Hematology ... #Diagnosis #Comparison
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
Thrombocytopenia ... the critically ill ... coagulation defects. 1) ... AFLP #obstetrics #hematology ... #diagnosis #table
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus
Clinical Domains:
 • Constitutional domain: Fever
 • Cutaneous domain: Non-scarring
Classification Criteria ... domain: Leukopenia, Thrombocytopenia ... nephritis, Class Ill ... Erythematosus #diagnosis ... #rheumatology
Who to test for BRCA 1/2?
Female Breast Cancer:
 • ≤ 45-50 years at diagnosis
 • Triple
test for BRCA 1/ ... 45-50 years at diagnosis ... relative meeting criteria ... #indications #oncology ... Cancer #screening #diagnosis
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
minimal tumor burden Diagnosis ... with anemia or thrombocytopenia ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc ... #diagnosis #management
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
-1 and IL-6, leading ... leukopenia, anemia, and thrombocytopenia ... Histopathologic criteria ... Activation #Syndrome #Diagnosis ... #Rheumatology
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
• Leukocytosis Diagnosis ... - Yamaguchi criteria ... 5 of the below criteria ... should be major: 1. ... #rheumatology #
Rigors And Bacteremia - Overview

• Rigors are a response to the release of cytokines and prostaglandins
• Chills • Thrombocytopenia ... PATHOPHYSIOLOGY: ... -1, IFN, IL-6): ... Rigors #Bacteremia #Pathophysiology ... InfectiousDiseases #Diagnosis