23 results
Hemophagocytic Lymphohistiocytosis (HLH)
Clinical Features: Fever, Splenomegaly, Hepatomegaly, Lymphadenopathy, Confusion
Classic lab findings in HLH: ↑↑ ferritin, Anemia,
ferritin, Anemia, Thrombocytopenia ... activity, ↑ soluble IL ... -2 receptor Diagnostic ... ): Molecular diagnosis ... #hematology #criteria
4T Score for Heparin-Induced Thrombocytopenia

Interpretation of the 4T score:
0-3 points:  Low probability (<<1%)
  -
Heparin-Induced Thrombocytopenia ... probability (<<1% ... HeparinInduced #Thrombocytopenia ... #Diagnosis #Criteria ... #Hematology
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Thrombocytopenia ... the critically ill ... coagulation defects. 1) ... Obstetrics #OBGyn #Hematology ... #Diagnosis #Comparison
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
Thrombocytopenia ... the critically ill ... coagulation defects. 1) ... AFLP #obstetrics #hematology ... #diagnosis #table
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus
Clinical Domains:
 • Constitutional domain: Fever
 • Cutaneous domain: Non-scarring
Classification Criteria ... domain: Leukopenia, Thrombocytopenia ... nephritis, Class Ill ... Erythematosus #diagnosis ... #rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
-1 and IL-6, leading ... leukopenia, anemia, and thrombocytopenia ... Histopathologic criteria ... Activation #Syndrome #Diagnosis ... #Rheumatology
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
• Leukocytosis Diagnosis ... - Yamaguchi criteria ... 5 of the below criteria ... should be major: 1. ... #rheumatology #
Rigors And Bacteremia - Overview

• Rigors are a response to the release of cytokines and prostaglandins
• Chills • Thrombocytopenia ... PATHOPHYSIOLOGY: ... -1, IFN, IL-6): ... Rigors #Bacteremia #Pathophysiology ... InfectiousDiseases #Diagnosis
Scurvy (Vitamin C Deficiency) - Diagnosis and Management

Vitamin C is required for hydroxylation of proline residues
Deficiency) - Diagnosis ... • Persons with psychiatric ... Psychiatric symptoms ... cutaneous vasculitis, thrombocytopenia ... Supplementation with 1
Attention Deficit Hyperactive Disorder (ADHD): Pathogenesis and clinical findings
 - For diagnosis, must have either 26
at > 17 years old ... than females (4:1) ... BehavioralDisorder #Pathophysiology ... #signs #psychiatry ... #criteria