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diagnosis hematology management differential clinical syndrome algorithm oncology physicalexam treatment table comparison workup causes classification pathophysiology criteria disease lupus neurology
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... • Lupus (SLE): ANA ... (anti-nuclear antibody ... Myositis: Anti-JO-1, ... Polymerase Ill
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
ANA (Antinuclear ... Antibody) and ANCA ... erythematosus 1. ... dermatomyositis 1. ... antibodies #diagnosis #rheumatology
Mixing Study • Clotting tests can be abnormal due to either a clotting factor deficiency, or
activity (e.g. antibody ... to be normal. 1: ... 1 Mix of Patient's ... Study #diagnosis #hematology ... pathophysiology #hematology
4T Score for Heparin-Induced Thrombocytopenia Interpretation of the 4T score: 0-3 points: Low probability (<<1%) -
probability (<<1% ... check anti-PF4 antibody ... check anti-PF4 antibody ... Diagnosis #Criteria #Hematology
Nodular pattern 1. Hypersensitivity pneumonitis: ill defined centrilobular nodules. 2. Miliary TB: random nodules 3. Sarcoidosis: nodules with perilymphatic
Nodular pattern 1. ... Hypersensitivity pneumonitis ... : ill defined centrilobular ... Hypersensitivity pneumonitis ... next to pleura and
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
Disease Associations ANA ... Drug-induced SLE Anti-Jo-1 ... polyangiitis U1-RNP antibody ... disease Endomyseal antibody ... diagnosis #table #rheumatology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... Inflammatory Conditions: Rheumatologic ... Vasculitides, IBD ... Acute bacterial and ... Diagnosis #Algorithm #hematology
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
Inflammatory and ... hemoglobinuria • Antibody-mediated ... Differential #Diagnosis #Hematology
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
gangrenosum • IBD ... Antiphospholipid-antibody ... Sarcoidosis #dermatology ... differential #diagnosis #rheumatology
Immune Reactions and Immunosuppressant Drugs Glucocorticoids - Inhibition of cytokine synthesis, e.g., IL-1, IL-2 Muromonab-CD3 - Monoclonal antibody Calcineurin
Immune Reactions and ... synthesis, e.g., IL ... -1, IL-2 Muromonab-CD3 ... - Monoclonal antibody ... Suppression of IL
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