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diagnosis rheumatology radiology sle ctchest differential erythematosus neurology pulmonary radiologyassistant summary systemic algorithm barre criticalcare druginduced foamed guillain interstitial lung
Interstitial Lung Diseases (ILD) Exposure-Related ILD (a.k.a. extrinsic allergic alveolitis): • Hypersensitivity pneumonitis, Farmer's lung, Bird
Hypersensitivity pneumonitis ... ILD caused by inhalation ... Polymyositis-dermatomyositis, Lupus ... Churg Strauss syndrome ... differential #pulmonary #causes
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... Prognosis: Usually mild ... 40, F:M 9:1 • Clinical ... - Positive in up ... Usual therapeutic management
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
40, F:M 9:1 • Clinical ... - Positive in up ... Positive in 60-80% of cases ... life-threatening • Treatment ... of SLE • Evolution
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... Anti-UI-ribonucleoprotein ... severe disease Treatment ... : • Mild disease ... #rheumatology #management
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Demyelinating Syndrome ... autoantibodies that will cause ... cerebritis #diagnosis #management ... #treatment
Cryptogenic Organizing Pneumonia (COP) Cryptogenic Organizing Pneumonia Overview: • Idiopathic form of organizing pneumonia • formerly BOOP
Unknown • 6-7 cases ... Organizing Pneumonia - Clinical ... Organizing Pneumonia Treatment ... BOOP #pulmonary #ILD ... #diagnosis #management
REBEL Review 99: Serotonin Syndrome via Yosuf Alam, MSIV Presentation: Altered mentd status, Seizures, Myoclonus, Hypertension, Hyperthermia
99: Serotonin Syndrome ... Hyperthermia (most common cause ... Diagnosis: Clinical ... Cornerstone of treatment ... fluid hydration; evaluation
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
disease • Systemic lupus ... Clinical Presentation ... SJIA], systemic lupus ... Treatment: • Corticosteroids ... #Diagnosis #Management
Lymphocytic interstitial pneumonitis or LIP is uncommon, being seen mainly in patients with autoimmune disease, particularly
Lymphocytic interstitial pneumonitis ... gren's syndrome, ... with Sjogren's syndrome ... #Clinical #Radiology ... #ILD #RadiologyAssistant
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... Treatment: • ... inhibitors under evaluation ... Lymphohistiocytosis #diagnosis #management
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