21 results
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Physical Exam/Signs ... • Richter’s Syndrome ... ’s lymphoma or acute ... leukemia • Sezary syndrome ... #oncology #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
, CLL Acute leukemias ... ALL (Acute Lymphoblastic ... develop leukostasis syndrome ... • Tumor lysis syndrome ... #Oncology #Diagnosis
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... transformation to acute ... Allogeneic stem cell ... Myelodysplastic #Syndrome ... #oncology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Differential Diagnosis Algorithm ... for workup, including ... Inflammatory Conditions: Rheumatologic ... Kawasaki, Nephrotic syndrome ... Differential #Diagnosis #Algorithm
Algorithm for the Evaluation of Chronic Diarrhea (< 7 days)
Exclude:
1. Causes of acute diarrhea
2. Lactose intolerance
3.
Causes of acute ... Irritable bowel syndrome ... Malabsorption syndromes ... Irritable bowel syndrome ... #algorithm #workup
Hypophosphatemia - Differential Diagnosis Algorithm
Appropriately Low Kidney Phosphate Excretion:
 • Decreased GI Absorption: Chronic Diarrhea, Antacids,
Shift: Refeeding Syndrome ... , Acute Respiratory ... Tumor Genesis Syndrome ... FGF23: Fanconi Syndrome ... nephrology #phosphorus #workup
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
Acute Kidney Injury ... - AKI Workup Algorithm ... clinical context and signs ... Abdominal compartment syndrome ... • Cardio-renal syndrome
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Myelodysplastic Syndromes ... Myelodysplastic syndromes ... formed or don’t work ... ) • Felty Syndrome ... #oncology
Tumor Lysis Syndrome
An acute, life-threatening condition that appears within 7 days of starting cytotoxic therapies in
Tumor Lysis Syndrome ... An acute, life-threatening ... #Tumor #Lysis #Syndrome ... #TLS #oncology ... #management #UricAcid
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... • Induce blast cell ... Differentiation #Syndrome ... APML #diagnosis #management ... #hematology #oncology