847 results
Lupus Nephritis - Diagnostic approach to kidney disease associated with systemic lupus erythematosus (SLE)
SLE patient develops
Lupus Nephritis ... with systemic lupus ... new: • Proteinuria ... with evidence of proteinuria ... Disease (5%) #Lupus
Algorithm for the Treatment of Membranous Lupus Nephritis
Sub-nephrotic-range proteinuria (<3.5g/d, normal serum albumin) and Preserved kidney
of Membranous Lupus ... Sub-nephrotic-range proteinuria ... treat non-renal SLE ... treat extra-renal SLE ... #Membranous #Lupus
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus
Clinical Domains:
 • Constitutional domain: Fever
 • Cutaneous domain: Non-scarring
Criteria for Systemic Lupus ... Acute cutaneous lupus ... Renal domain: Proteinuria ... Classification #Criteria #SLE ... #Systemic #Lupus
Management of Lupus Nephritis
Lupus nephritis (LN) in 10 to 40% of SLE
Hallmark = proteinuria 20.5 g/g
Management of Lupus ... Nephritis Lupus ... in 10 to 40% of SLE ... Hallmark = proteinuria ... therapy Goal: proteinuria
Top 10 situations when to think about lupus
1) Inflammatory joint pain (especially in the wrists and
to think about lupus ... the discovery of proteinuria ... pericarditis » is...lupus ... children (pediatric SLE ... #diagnosis #sle
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... (non-nephrotic proteinuria ... nephrotic-range proteinuria ... : Drug induced SLE ... SSA can rule in SLE
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
• Hematuria, proteinuria ... inflammation Others: • Lupus ... such as systemic lupus ... vasculitis, and SLE
Clinical Manifestations of Systemic Lupus Erythematosus (SLE)

#Systemic #Lupus #Erythematosus #SLE #Manifestations #Signs #Symptoms #Rheumatology #Diagnosis
Manifestations of Systemic Lupus ... Erythematosus (SLE ... ) #Systemic #Lupus ... Erythematosus #SLE
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
antibodies and Systemic lupus ... Farr assay) and lupus ... Highly specific for SLE ... & drug-induced lupus ... , neonatal lupus
ANA Patterns and Associated Rheumatic Diseases:
 • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
Homogeneous: Systemic lupus ... erythematosus (SLE ... , Drug-induced Lupus ... erythematosus (SLE ... erythematosus (SLE