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diagnosis coagulation differential causes hepatology management abnormal algorithm aptt laboratory liver pathophysiology blood cascade clinical clots dic disseminated echocardiogram embolism
Causes of Prolonged PT (INR), Prolonged PTT • Prolonged PT (INR), Prolonged PTT • Prolonged PT
PT (INR), Prolonged ... PT (INR), Prolonged ... PT (INR), Normal ... PTT, Normal PT ... Algorithm #Causes #Hematology
How to Evaluate an Abnormal APTT Step 1: Is the PT or APTT Artifactually Prolonged? Step 2: Is
Step 1: Is the PT ... Artifactually Prolonged ... Heparin, or Direct Thrombin ... Prolonging the PT ... #diagnosis #hematology
Algorithm for Investigation of Abnormal Coagulation Tests - Prolonged PT - Prolonged aPTT and Prolonged PT - Prolonged aPTT Dr.
Coagulation Tests - Prolonged ... PT - Prolonged ... aPTT and Prolonged ... PT - Prolonged ... APTT #Laboratory #Hematology
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Causes of Abnormal PT ... Prothrombin Time (PT ... PT too 2. ... drugs e.g. direct thrombin ... #differential #hematology
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
Diagnosis for a Prolonged ... PT and aPTT If ... the PT and the ... drugs (e.g. direct thrombin ... #differential #hematology
Von Willebrand Disease - Most common inherited bleeding disorder Clinical • Easy bruising •
bleeding • Prolonged ... 2B) • Normal PT ... • Normal aPTT (prolonged ... Disease #Diagnosis #Hematology
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
at the site of injury ... FVa to generate thrombin ... Thrombin, then primes ... #clot #PT #PTT ... diagnosis #models #hematology
ISTH Scoring System for Disseminated Intravascular Coagulation (DIC) Platelet count: • Expected: Low (or normal) • Elevation
• Elevation in thrombin ... platelet aggregation PT ... can accelerate thrombin ... using INR use PT ... Scoring #diagnosis #hematology
This 24M presented with acute onset CP/SOB, hypoxia, HR 150s. What's the diagnosis? Treatment options? Hint:
Thrombus in transit ... Pt had extensive ... Echocardiogram #A4C ... PulmonaryEmbolism #Thrombus
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 Pancytopenia - Differential Diagnosis Algorithm • 12-13 g/dL, • ANC < 1800/uL, • platelet < 150,000/uL Initial
12-13 g/dL, • ANC ... iron studies, PT ... Diagnosis #Algorithm #hematology
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