16 results
Algorithm for Investigation of Abnormal Coagulation Tests
- Prolonged PT
- Prolonged aPTT and Prolonged PT
- Prolonged aPTT

Dr.
Coagulation Tests ... - Prolonged PT ... and Prolonged PT ... #Laboratory #Hematology ... #Diagnosis #Workup
ISTH Scoring System for Disseminated Intravascular Coagulation (DIC)
Platelet count:
 • Expected: Low (or normal)
 • Elevation
Intravascular Coagulation ... platelet aggregation PT ... using INR use PT ... ISTH #Scoring #diagnosis ... #hematology #laboratory
Effect of Anticoagulants on Coagulation Tests
PT / INR, aPTT, Anti-Xa Activity, Activated Clotting Time, Thrombin Time,
Anticoagulants on Coagulation ... Tests PT / INR, ... Clotting Time, Thrombin ... Anticoagulation #Testing #Diagnosis ... #Laboratory #Effects
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
• Prolonged PT ... • Increased thrombin ... organ damage Clinical ... venipuncture sites Laboratory ... #diagnosis #causes
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Causes of Abnormal ... drugs e.g. direct thrombin ... intravascular coagulation ... Jcortesizaguirr #Abnormal ... #Causes #diagnosis
This 24M presented with acute onset CP/SOB, hypoxia, HR 150s. What's the diagnosis? Treatment options? Hint:
What's the diagnosis ... Pt had extensive ... 3 d later with normal ... #Clinical #POCUS ... Echocardiogram #A4C
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
PT/NORMAL PTT: ... PT/ABNORMAL PTT ... PT/NORMAL PTT: ... PT/ABNORMAL PTT ... warfarin, direct thrombin
Von Willebrand Disease - Most common inherited bleeding disorder 
Clinical 
 • Easy bruising 
 •
bleeding disorder Clinical ... GI. uterine) Laboratory ... • Normal platelet ... PT/INR • Normal ... VonWillebrand #Disease #Diagnosis
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
Differential Diagnosis ... drugs (e.g. direct thrombin ... amyloidosis #Abnormal ... #Causes #diagnosis ... differential #hematology #coagulation
Commonly Observed Laboratory Findings in Hepatic / Liver Failure
 - Elevated conjugated and unconjugated bilirubin -
Commonly Observed Laboratory ... liver glycogen stores ... - Prolonged PT ... Hepatic #Hepatology #Laboratory ... #Diagnosis #Testing