21 results
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
pathophysiologic causes ... Post-strep GN, Lupus ... • Limited to Kidney ... Glomerulonephritis #Vasculitis ... #differential #diagnosis
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Diagnosis Algorithm ... Infection - Vasculitis ... (lupus, RA, Sjogren's ... #Algorithm #Causes
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
tract, and often causes ... inflammation Others: • Lupus ... mucositis - Rash ... such as systemic lupus ... Kidneys -> glomerulonephritis
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm
Acute Kidney Injury (AKI) - Acute increase
Kidney Injury (AKI ... - Differential Diagnosis ... Algorithm Acute Kidney ... IgA, post-strep, lupus ... #Algorithm #Causes
Causes of Fever of Unknown Origin (FUO) - Differential Diagnosis
 • Infection: Extrapulmonary tuberculosis, Abscess, Endocarditis,
- Differential Diagnosis ... Brucellosis, Q fever, EBV ... . autoimmune): Lupus ... the most common vasculitis ... #Differential #Diagnosis
Acute Kidney Injury (AKI) - Differential Diagnosis Framework
Pre-Renal:
 • Hypovolemia, Cardiorenal, Distributive Shock, HRS, Hypercalcemia, Renal
Acute Kidney Injury ... - Differential Diagnosis ... Emboli, Thrombosis, Vasculitis ... GN: ANCA, Anti-GBM ... #nephrology #causes
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
hair follicles -> causes ... plugging -> Discoid Rash ... Malar (butterfly) Rash ... Livedo Reticularis, Vasculitis ... pathophysiology #diagnosis
Acute Kidney Injury - Classification
Prerenal:
 • Dehydration
 • Heart failure (a.k.a. cardiorenal syndrome)
 • Liver failure
Acute Kidney Injury ... - Small vessel vasculitis ... tubular necrosis (causes ... : sepsis, meds, ... Classification #diagnosis
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... ANCA-associated vasculitis ... C4) • ds-DNA: Kidney ... induced SLE • Kidney ... Erythematosus #Diagnosis
Causes of Pharyngitis - Differential Diagnosis
Infectious:
 • Bacterial: Group A Strep, Group B and C Strep,
Causes of Pharyngitis ... Syphilis • Viral: EBV ... Viruses Autoimmune: Lupus ... syndrome, ANCA vasculitis ... #Causes