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management differential lupus dermatology erythematosus disease myositis signs symptoms systemic vasculitis autoimmune druginduced myopathy skin skinrash treatment activation agitation ana
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Rash • Human ... infection Malar rash ... Antiphospholipid-antibody syndrome ... differential #diagnosis ... #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... Photosensitivity, Butterfly rash ... Demyelinating syndromes ... lesions Abdominal pain ... #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
) - Diagnosis and ... 40, F:M 9:1 • Clinical ... Manifestations: Malar rash ... Erythematosus #Diagnosis ... Management #Summary #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
NPSLE rare, Malar rash ... Manifestations: Malar rash ... #comparison #table ... #rheumatology # ... diagnosis #management
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
can present with rash ... including heliotrope rash ... anti-synthetase syndrome ... Can also see mechanics ... #rheumatology
Top 10 situations when to think about lupus 1) Inflammatory joint pain (especially in the wrists and
Inflammatory joint pain ... and fingers, or pain ... everywhere) 2) A rash ... 6) An annular rash ... erythematosus #rheumatology
Myositis and Myopathies Polymyositis • Progressive, symmetric muscle weakness • Elevated CK, +Anti-Jo, +Anti-Mi2 Dermatomyositis
muscle weakness, rash ... Rheumatica • Pain ... Diffuse muscle pain ... #differential #diagnosis ... #comparison #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
evidence of (fatigue, rash ... eruption - Butterfly rash ... Photosensitive rash ... Arthritis: • Joint pain ... Photosensitivity • Malar rash
Pediatric Inflammatory Multisystem Syndrome Temporally associated with SARS-CoV-2 infection (PIMS-TS) Clinical features all: fever > 101.3 F most: oxygen
Inflammatory Multisystem Syndrome ... infection (PIMS-TS) Clinical ... some: abdominal pain ... conjunctivitis, cough, rash ... #coronavirus #diagnosis
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
• Fever is the main ... Petechial or purpuric rash ... erythematosus [SLE ... #Diagnosis #Management ... #Hematology #Rheumatology
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