16 results
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... and Management ... Manifestations: Malar rash ... Workup: - ANA ... #Summary #rheumatology
I’M DAMN SHARP - Lupus Diagnosis Mnemonic
I  	 Immunoglobulins (Anti-dsDNA, Anti-Sm, Anti-phospholipid)
M 	 Malar Rash
D
Anti-phospholipid) M Malar Rash ... D Discoid Rash ... Antinuclear Antibody (ANA ... #IMDAMNSHARP #sle ... #erythematosus
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
NPSLE rare, Malar rash ... Workup: - ANA ... Manifestations: Malar rash ... Workup: - ANA ... #sle #comparison
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
evidence of (fatigue, rash ... eruption - Butterfly rash ... rashErythematous ... Photosensitivity • Malar rash ... Serositis Labs: • ANA
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
ANA (Antinuclear ... ) • Systemic lupus ... erythematosus ... in drug-induced SLE ... antibodies #diagnosis #rheumatology
SOAP BRAIN MD Mnemonic for Systemic Lupus Erythematosus (SLE)

S - Serositis (Pleuritis, Pericarditis)
O - Oral Ulcers
A
Erythematosus ( ... Involvement A - ANA ... Symptoms M - Malar rash ... D - Discoid rash ... #SLE #Rheumatology
Top 10 situations when to think about lupus
1) Inflammatory joint pain (especially in the wrists and
everywhere) 2) A rash ... pleurisy (search ANA ... annular rash on ... person (search ANA ... cytopenia (search ANA
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Systemic Lupus Erythematosus ... 69% - Malar rash ... Auto-Antibodies: - ANA ... #Erythematosus ... #differential #rheumatology
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... Antinuclear (ANA ... #Erythematosus ... #rheumatology # ... management
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
mucositis - Rash ... such as systemic lupus ... erythematosus, ... SLE) • Urinalysis ... differential #diagnosis #rheumatology