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Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Approach to Anemia - Differential ... Diagnosis Algorithm Blood ... of: Decreased Reticulocytes ... Normal / Decreased Reticulocytes ... Classification #Approach #Differential
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
Reticulocyte Production ... the peripheral blood ... including chronic blood ... > 3: • Acute blood ... hematology #anemia #differential
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
normocytic, ↑ reticulocytes ... type ± C3d • Blood ... smear: Differential
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... - Peripheral Blood ... abnormal RBCs - Reticulocyte ... #Hemolysis #Differential
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis Baseline Investigations: full blood count with differential,
Algorithm and Differential ... Investigations: full blood ... count with differential ... LDH, platelets, reticulocytes ... screen, including blood
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased Heme Synthesis or
Volume (MCV) - Differential ... Causes: Chronic Blood ... +/- increased reticulocytes ... #elevatedMCV #Differential
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell ( ... syndrome, Increased reticulocyte ... key #diagnosis #differential
Calculating a Reticulocyte Index (RI) Reticulocyte Index = Absolute Reticulocyte Count / Maturation Correction Absolute Reticulocyte Count =
Calculating a Reticulocyte ... Index (RI) Reticulocyte ... Index = Absolute Reticulocyte ... Count = % of reticulocytes ... SatyaPatelMD #Reticulocyte
Pancytopenia - Differential Diagnosis Algorithm • 12-13 g/dL, • ANC < 1800/uL, • platelet < 150,000/uL Initial
Pancytopenia - Differential ... peripheral smear, reticulocyte ... Production (↓ reticulocytes ... (hemolysis, ↑ reticulocytes ... #Pancytopenia #Differential
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Reticulocyte count ... in peripheral blood ... High in acute blood ... Corrected reticulocyte ... count OR reticulocyte
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