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Pancytopenia - Differential Diagnosis Algorithm • 12-13 g/dL, • ANC < 1800/uL, • platelet < 150,000/uL Initial
Pancytopenia - Differential ... peripheral smear, reticulocyte ... Production (↓ reticulocytes ... (hemolysis, ↑ reticulocytes ... #Pancytopenia #Differential
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm Suspected TMA: Unexplained thrombocytopenia + MAHA
Microangiopathy (TMA) - Differential ... labs: CBC, BMP, Reticulocytes ... schistocytes > 1% • ↑ Reticulocyte ... Microangiopathy #TMA #Differential
Isolated Hyperbilirubinemia - Differential Diagnosis Algorithm Direct Hyperbilirubinemia: Dubin-Johnson Syndrome, Rotor Syndrome Indirect Hyperbilirubinemia: - Trauma, Hematoma,
Hyperbilirubinemia - Differential ... , Haptoglobin, Reticulocyte ... , Haptoglobin, Reticulocyte ... Hyperbilirubinemia #Isolated #Differential
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Approach to Anemia - Differential ... of: Decreased Reticulocytes ... Normal / Decreased Reticulocytes ... Destruction - Increased Reticulocytes ... Classification #Approach #Differential
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
Reticulocyte Production ... days) it takes a reticulocyte ... EricsMedicalLectures/ #Reticulocyte ... hematology #anemia #differential
General Approach to Anemia - Differential Diagnosis Framework 1) Check reticulocyte count to determine if hypo/hyper-proliferative 2) Exclude
Approach to Anemia - Differential ... Framework 1) Check reticulocyte ... uw_IMresidency #anemia #differential ... hematology #algorithm #reticulocyte
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
Hemolytic Anemias - Differential ... bilirubin • ↑ Reticulocytes ... Hemolytic #Anemias #Differential
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... abnormal RBCs - Reticulocyte ... #Hemolysis #Differential
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
normocytic, ↑ reticulocytes ... • Blood smear: Differential
Calculating a Reticulocyte Index (RI) Reticulocyte Index = Absolute Reticulocyte Count / Maturation Correction Absolute Reticulocyte Count =
Calculating a Reticulocyte ... Index (RI) Reticulocyte ... Index = Absolute Reticulocyte ... Count = % of reticulocytes ... SatyaPatelMD #Reticulocyte
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