46 results
Lupus Nephritis Primer
Class I - Minimal Mesangial
Class II - Mesangial Proliferative
Class Ill - Focal Proliferative
Class IV
Ill - Focal Proliferative ... Lupus #Nephritis #SLE ... Classification #Classes ... #differential #diagnosis ... #management #nephrology
Management of Lupus Nephritis
Lupus nephritis (LN) in 10 to 40% of SLE
Hallmark = proteinuria 20.5 g/g
Management of Lupus ... in 10 to 40% of SLE ... #treatment #management ... #rheumatology # ... nephrology
Generalized Weakness - Differential Diagnosis Framework
"l feel weak":
 • Infectious: Influenza, EBV, PNA, Bacteremia, Sepsis
 •
- Differential Diagnosis ... valves, COPD, ILD ... body-), PMR, RA, SLE ... #Differential #Diagnosis ... #causes #neurology
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
- Differential Diagnosis ... and Management ... levels > 8mg/dL See ... #Management #Summary ... #causes #treatment
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
10% of all lupus cases ... Prognosis: Usually mild ... Discontinuation of causal ... Positive in 60-80% of cases ... #diagnosis #management
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
Causes of Knee Effusions ... - Differential Diagnosis ... arthritis - SLE ... Knee #Effusions #causes ... #msk #physicalexam
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
and Management ... : 70 years old, ... ~10,000 new cases ... #Management #treatment ... #hematology #oncology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
) - Diagnosis and ... Management Summary ... Positive in 60-80% of cases ... Erythematosus #Diagnosis ... #rheumatology
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY

RED FLAGS - In all cases there are specific
markers which
FLAGS - In all cases ... Non-accidental Injury ... splenomegaly, abnormal neurology ... , back pain Haematology ... Peds #Pediatrics #Diagnosis
Dermatological semiology of Cutaneous Vasculitis 

Clinicopathologic correlations
 • Purpura, papules, pustules, necrosis: involvement of small vessels
Identification of causes ... disease (10%) : SLE ... 2%) • Other: IBD ... Vasculitis #dermpath #dermatology ... signs #lesions #diagnosis