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management differential syndrome algorithm oncology clinical neurology rheumatology hepatology photo comparison rash reactions skinrash table barre blood chronic classification dermatomyositis
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... Infectious: • Acute ... Inflammatory: • IBD ... effect following treatment ... #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
- Differential Diagnosis ... → Refer to hematology ... Rebound effect from treatment ... #Differential #Diagnosis ... #Algorithm #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
: 70 years old, ... ~10,000 new cases ... transformation to acute ... #Management #treatment ... #hematology #oncology
Von Willebrand Disease - Most common inherited bleeding disorder Clinical • Easy bruising •
bruising • Skin ... platelet count (mild ... factor VIII) Treatment ... VonWillebrand #Disease #Diagnosis ... #Hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... purple, hemorrhagic skin ... - APLS • Acute ... #hematology #rheumatology ... #nonpalpable #dermatology
Acute Kidney Injury (AKI) in Patients with Cancer Cancer Related • Hypercalcemia • Intravenous contrast •
Acute Kidney Injury ... change disease • Hematologic ... malignancies Treatment ... #Differential #Diagnosis ... Classification #Nephrology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... in those with CLD ... months without treatment ... Drug-Induced Liver Injury ... gastroenterology #management #diagnosis
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
toxic aetiology: Skin ... non-essential drug/HDS treatments ... for alternative causes ... dechallenge • Acute ... #hepatology
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Definition: • Severe adverse drug reaction, characterized by
Edema in 70% of cases ... • SJS/TEN • Acute ... withdrawal • Mild ... disease: symptomatic treatment ... DRESS #Syndrome #dermatology
Leg Pain - Differential Diagnosis Framework Bone/Joint Causes of Leg Pain: • Fracture • Arthritis • Gout/pseudogout
- Differential Diagnosis ... • Bursitis • IBD ... Repetitive strain injury ... Trauma • Crush injury ... Immobilization) • Acute
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