30 results
Thrombotic Microangiopathies In Systemic Lupus Erythematosus

Dr. Laurent ARNAUD @Lupusreference

#TMAs #Thrombotic #Microangiopathies #Systemic #Lupus #Erythematosus #SLE #hematology
Thrombotic Microangiopathies ... In Systemic Lupus ... Lupusreference #TMAs #Thrombotic ... Erythematosus #SLE ... #hematology #rheumatology
Renal Involvement in Systemic Lupus Erythematosus

Dr. Laurent ARNAUD @Lupusreference

#Renal #diseases #SLE #Systemic #Lupus #Erythematosus #venn #nephrology
Involvement in Systemic Lupus ... Renal #diseases #SLE ... #Systemic #Lupus ... Erythematosus #venn #nephrology ... classification #types #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... vasculopathy, thrombosis ... Induction Rx: high-dose ... #CNS #neurology ... #rheumatology #
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... • Specific for SLE ... Severe disease- high ... #Systemic #Lupus ... Summary #diagnosis #rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... complements and a high ... Non-autoimmune rheumatologic ... : Drug induced SLE ... Erythematosus #Diagnosis #Rheumatology
Thrombotic Microangiopathy - TTP VS HUS

Big picture points : Often hard to differentiate the two entities,
Thrombotic Microangiopathy ... implications : TTP has high ... testing for TTP #Thrombotic ... Diagnosis #Table #Hematology
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Malar rash • SLE ... IBD • RA • SLE ... lesions • Discoid lupus ... Sarcoidosis #dermatology ... differential #diagnosis #rheumatology
Thrombotic Microangiopathy - TMAs
1. Not all MAHAs are due to TMAs but (almost) all TMAs cause
Thrombotic Microangiopathy ... catastrophic APS, SRC, SLE ... There is a high ... @AnnKumfer #Thrombotic ... Microangiopathy #TMAs #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
syndrome - Thrombotic ... microangiopathy: Thrombotic ... usually IgG) (e.g. lupus ... differential #diagnosis #hematology
4-T Score for the Likelihood of Heparin Induced Thrombocytopenia
 - Thrombocytopenia - Compare the highest platelet
count
platelet fall or thrombosis ... ) - Thrombosis ... 6 to 8 points: High ... Likelihood #Diagnosis #Hematology