18 results
Cutaneous manifestations associated with myelodysplastic syndrome
 • Myeloid hemopathy with the most frequent skin lesions (20%)
Cutaneous manifestations ... most frequent skin ... dermatomyositis, SLE ... Calmettes #Cutaneous ... differential #diagnosis #dermatology
Cutaneous Manifestations of Monoclonal Gammopathy
 • Extravascular lg Deposits: Systemic amyloidosis, Nodular amyloidosis, Macroglobulinoderma, Follicular hyperkeratotic
Cutaneous Manifestations ... Extravascular lg Deposits: Systemic ... monoclonal #gammopathy #Cutaneous ... #manifestations ... #dermatology #skin
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... Manifestations ... response -> Subacute cutaneous ... inflammation on skin ... #Manifestations
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
vs SLE Drug Induced ... Rare (SSA+ for cutaneous ... rare), Topics for cutaneous-DIL ... months to years) Systemic ... Photosensitivity, Alopecia
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... Associated with skin ... manifestations ... block • Sjogren syndrome ... #Lupus #Erythematosus
Allopecia - Differential Diagnosis Framework for Hair Loss

Localized / Focal Hair Loss Pattern:
 • Scarring Alopecia:
Capitis - Skin ... Disease: Discoid lupus ... , Loose anagen syndrome ... Vitamin D levels Systemic ... Differential #Diagnosis #dermatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... 3rd Decade Skin ... and permanent alopecia ... • Nonscarring alopecia ... #Systemic #Lupus
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Alpha & Mu) Skin ... Manifestations: ... gangrenosum • Cutaneous ... thrombosis+Pulm HTN+skin ... to cold IgG • Lupus
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
lupus erythematosus ... main clinical manifestation ... • Hemorrhagic manifestations ... lupus erythematosus ... [SLE], AOSD) •
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
associated with systemic ... Musculoskeletal system ... Most common extra cutaneous ... - Lupus - Leukemia ... #diagnosis #dermatology