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management rheumatology neurology differential syndrome erythematosus hematology systemic druginduced gravis hyperkalemia myasthenia nephritis oncology potassium rhabdomyolysis skin types vasculitis workup
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
(SLE) - Diagnosis ... and Management Summary ... 40, F:M 9:1 • Clinical ... Positive in 60-80% of cases ... life-threatening • Treatment
Lupus Nephritis Primer Class I - Minimal Mesangial Class II - Mesangial Proliferative Class Ill - Focal Proliferative Class IV
#Nephritis #SLE ... #Classification ... #Classes #differential ... #diagnosis #management ... #nephrology
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... - Summary Antinuclear ... severe disease & renal ... severe disease Treatment ... #Summary #diagnosis
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... ) Clinical Manifestations ... autoantibodies that will cause ... Erythematosus #SLE ... #CNS #neurology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... Discontinuation of causal ... 40, F:M 9:1 • Clinical ... life-threatening • Treatment ... #rheumatology #diagnosis
Management of Lupus Nephritis Lupus nephritis (LN) in 10 to 40% of SLE Hallmark = proteinuria 20.5 g/g
in 10 to 40% of SLE ... or 0.5 g/day → renal ... by 12 months Classification ... Nephritis #Management #treatment ... #rheumatology #nephrology
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... Erythematosus Clinical ... hemolysis • Renal ... #Criteria #SLE ... Erythematosus #diagnosis
Rhabdomyolysis - Differential Diagnosis and Management Summary Trauma: • Immobilization, Crush iniury, Compartment syndrome, Electrical injury Exertional: •
- Differential Diagnosis ... and Management Summary ... levels > 8mg/dL See ... #Management #Summary ... #causes #treatment
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... ) Suspect: Clinical ... Skin Disease Classification ... Differential Diagnosis ... Erythematosus #Diagnosis
Staphylococcus-associated GlomeruloNephritis - Diagnosis and Management Summary CLINICAL • Nephritic syndrome (Casts) • Marked proteinuria (may be
and Management Summary ... CLINICAL • Nephritic ... syndrome (Casts ... deposits common TREATMENT ... GlomeruloNephritis #nephrology
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