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management neurology rheumatology differential syndrome hematology erythematosus systemic classification druginduced gravis rhabdomyolysis signs skin symptoms workup abg acid acidbase acidosis
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
(SLE) - Diagnosis ... and Management Summary ... 40, F:M 9:1 • Clinical ... Positive in 60-80% of cases ... life-threatening • Treatment
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
rheumatoid arthritis, SLE ... Clinical Picture ... Diagnosis - ... #Gravis #diagnosis ... #management #neurology
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... - Summary Antinuclear ... severe disease & renal ... severe disease Treatment ... #Summary #diagnosis
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... ) Clinical Manifestations ... autoantibodies that will cause ... Erythematosus #SLE ... #CNS #neurology
Myasthenia Gravis - Summary • an autoimmune disease of the postsynaptic neuromuscular junction associated with antibodies
- Summary • an ... : • Based on clinical ... More likely to cause ... - Improves clinical ... #management #neurology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... Discontinuation of causal ... 40, F:M 9:1 • Clinical ... life-threatening • Treatment ... #rheumatology #diagnosis
Generalized Weakness - Differential Diagnosis Framework "l feel weak": • Infectious: Influenza, EBV, PNA, Bacteremia, Sepsis •
- Differential Diagnosis ... Rhabdomyolysis, Critical ... NMJ disorder (Myasthenia ... body-), PMR, RA, SLE ... #causes #neurology
Rhabdomyolysis - Differential Diagnosis and Management Summary Trauma: • Immobilization, Crush iniury, Compartment syndrome, Electrical injury Exertional: •
- Differential Diagnosis ... and Management Summary ... levels > 8mg/dL See ... #Management #Summary ... #causes #treatment
Staphylococcus-associated GlomeruloNephritis - Diagnosis and Management Summary CLINICAL • Nephritic syndrome (Casts) • Marked proteinuria (may be
and Management Summary ... CLINICAL • Nephritic ... syndrome (Casts ... deposits common TREATMENT ... GlomeruloNephritis #nephrology
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
Optica (NMO) - Clinical ... disorders (Systemic lupus ... Sjögren syndrome, Myasthenia ... Manifestations #diagnosis ... #neurology #symptoms
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